Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750928 | 0.89 | ALDH1A1 (0.45) | PLAUCTDSP1HSD17B10GAAALDH1A1 | |
| SCHEMBL9009109 | 0.86 | ALDH1A1 (0.40) | PLAUCTDSP1HSD17B10GAAALDH1A1 | |
| SCHEMBL9009085 | 0.86 | ALDH1A1 (0.40) | PLAUCTDSP1HSD17B10GAAALDH1A1 | |
| SCHEMBL9572324 | 0.81 | PLAU (0.59) | PLAUCTDSP1NT5EHSD17B10GAA | |
| SCHEMBL24150455 | 0.80 | ALOX15 (0.46) | PLAUCTDSP1ALDH1A1ALOX15HPGD | |
| SCHEMBL19059655 | 0.80 | HSD17B10 (0.54) | CTDSP1HSD17B10GAAGFERALDH1A1 | |
| SCHEMBL13008672 | 0.78 | GAA (0.37) | PLAUCTDSP1NT5EHSD17B10GAA | |
| SCHEMBL6854234 | 0.77 | IDO1 (0.42) | PLAUNT5EHSD17B10GAAGFER | |
| Naphthoquinone SCHEMBL28157613 | 0.76 | NQO1 (0.45) | PLAUHSD17B10GAAALDH1A1ALOX15 | |
| SCHEMBL144625 | 0.75 | PTPN22 (0.60) | CTDSP1HSD17B10GAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011753-A | Polyamides Containing Hexafluoroisopropylidene Groups Which May Be Cured To Form Polybenzoxazoles | HOECHST CELANESE CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4939215-A | CHEMICAL AND RADIATION RESISTANCE; AIRCRAFT, ELECTRONICS | HOECHST CELANESE CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| US-4845183-A | MOLDING MATERIALS; FOR DIELECTRICS OR COATING SOLUTIONS; TOUGHNESS, FLEXIBILITY, TRANSPARENT | HOECHST CELANESE CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |
| EP-0317942-A2 | Heat resistant polyamides and polybenzoxazoles from bis-[(aminohydroxyphenyl hexafluoro-isopropyl] diphenyl ethers | HOECHST CELANESE CORPORATION (US) | 1989-05-31 | — | — | EP | disclosed |