Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | DTYMK | P23919 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 2/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180237 | 1.00 | GPR119 (0.36) | GPR119DTYMKPOLBKLK7KLK5 | |
| SCHEMBL4180242 | 1.00 | GPR119 (0.36) | GPR119DTYMKPOLBKLK7KLK5 | |
| SCHEMBL245192 | 0.84 | GRM5 (0.37) | GPR119DTYMKPOLBKLK7KLK5 | |
| SCHEMBL2447629 | 0.84 | GRM5 (0.37) | GPR119DTYMKPOLBKLK7KLK5 | |
| SCHEMBL7772596 | 0.83 | ELANE (0.46) | GPR119KLK7KLK5USP30 | |
| SCHEMBL4187151 | 0.82 | FAAH (0.35) | — | |
| SCHEMBL4187156 | 0.82 | FAAH (0.35) | — | |
| SCHEMBL4187147 | 0.82 | FAAH (0.35) | — | |
| SCHEMBL4189483 | 0.80 | GPR119 (0.35) | GPR119 | |
| SCHEMBL4189470 | 0.80 | GPR119 (0.35) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186868-A1 | Taxane Compound Having Azetidine Ring Structure | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090186868-A1 | Taxane Compound Having Azetidine Ring Structure | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1942109-A1 | TAXANE COMPOUND WITH AZETIDINE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186868-A1 | Taxane Compound Having Azetidine Ring Structure | ABCC1, AZI2, TPD52L2 | GPR119 1888/4885DTYMK 3748/4885POLB 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.