⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017195 | 1.00 | ALDH1A1 (0.56) | — | |
| SCHEMBL23875 | 1.00 | — | — | |
| SCHEMBL685153 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6645496 | 0.94 | — | — | |
| SCHEMBL28881845 | 0.94 | — | — | |
| SCHEMBL31518532 | 0.94 | — | — | |
| SCHEMBL27646234 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL2679632 | 0.94 | — | — | |
| Methyl Alcohol SCHEMBL17241953 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL1333597 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119776301-A | Alcohol dehydrogenase, recombinant genetically engineered bacterium and application thereof in asymmetric reduction of potential chiral carbonyl compounds | 杭州文德阶生物科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-115745764-B | Preparation method of milbelin intermediate | 重庆华森制药股份有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-115745764-A | Preparation method of milobalin intermediate | 重庆华森制药股份有限公司 | 2023-03-07 | — | — | CN | claimed |
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PSOMAGEN, INC. (US) | 2022-08-23 | — | — | US | claimed |
| US-20210128498-A1 | TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE | MACROGEN INC. (KR) | 2021-05-06 | — | — | US | claimed |
| EP-3668494-A1 | TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE | Psomagen, Inc. (US) | 2020-06-24 | — | — | EP | claimed |
| CN-111163761-A | Targeted drugs related to trimethylamine and/or trimethylamine-N-oxide | 普梭梅根公司 | 2020-05-15 | — | — | CN | claimed |
| CN-105853472-B | A kind of red shellfish essential oil and preparation method | 佛山科学技术学院 | 2019-10-25 | — | — | CN | claimed |
| WO-2019036507-A1 | TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE | uBiome, Inc. (US) | 2019-02-21 | — | — | WO | claimed |
| US-20190050525-A1 | RIESKE-TYPE OXYGENASE/REDUCTASE TARGETED DRUGS FOR DIAGNOSTIC AND TREATMENT OF DISEASES | PSOMAGEN, INC. | 2019-02-14 | — | — | US | claimed |
| CN-105853472-A | Arkshell essential oil and preparation method thereof | 佛山科学技术学院 | 2016-08-17 | — | — | CN | claimed |
| US-8471067-B2 | Stereoselective preparation of P-chiral four-co-ordinated phosphorus compound (o-Tolylphenylmethylphosphine oxide) by reacting chiral alcohol, chiral amine or chiral thiol, with P-chiral three-co-ordinated phosphorus compound, in presence of electrophile | UNIVERSITY COLLEGE DUBLIN (IE) | 2013-06-25 | — | — | US | claimed |
| US-20080255391-A1 | Chiral Phosphorus Compounds | UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND (IE) | 2008-10-16 | — | — | US | claimed |
| JP-2008501010-A | — | — | 2008-01-17 | — | — | JP | claimed |
| EP-1751170-A1 | CHIRAL PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2007-02-14 | — | — | EP | claimed |
| WO-2005118603-A1 | CHIRAL PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2005-12-15 | — | — | WO | claimed |
| US-20050154216-A1 | Novel enantiomeric compounds for treatment of cardiac arrhythmias and methods of use | ARYX THERAPEUTICS | 2005-07-14 | — | — | US | claimed |
| EP-4673214-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-01-07 | — | — | EP | disclosed |
| US-4374257-A | Novel ethers containing a lactone group and a chiral atom | ROUSSEL UCLAF (FR) | 1983-02-15 | — | — | US | disclosed |
| US-4265817-A | Novel chiral ethers and their use in resolution of alcohols and phenols | ROUSSEL UCLAF (FR) | 1981-05-05 | — | — | US | disclosed |