⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017195 | 1.00 | ALDH1A1 (0.56) | — | |
| SCHEMBL23875 | 1.00 | — | — | |
| SCHEMBL418078 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6645496 | 0.94 | — | — | |
| SCHEMBL28881845 | 0.94 | — | — | |
| SCHEMBL31518532 | 0.94 | — | — | |
| SCHEMBL27646234 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL2679632 | 0.94 | — | — | |
| Methyl Alcohol SCHEMBL17241953 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL1333597 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PSOMAGEN, INC. (US) | 2022-08-23 | — | — | US | claimed |
| US-20210128498-A1 | TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE | MACROGEN INC. (KR) | 2021-05-06 | — | — | US | claimed |
| EP-3668494-A1 | TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE | Psomagen, Inc. (US) | 2020-06-24 | — | — | EP | claimed |
| CN-111163761-A | Targeted drugs related to trimethylamine and/or trimethylamine-N-oxide | 普梭梅根公司 | 2020-05-15 | — | — | CN | claimed |
| WO-2019036507-A1 | TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE | uBiome, Inc. (US) | 2019-02-21 | — | — | WO | claimed |
| US-20190050525-A1 | RIESKE-TYPE OXYGENASE/REDUCTASE TARGETED DRUGS FOR DIAGNOSTIC AND TREATMENT OF DISEASES | PSOMAGEN, INC. | 2019-02-14 | — | — | US | claimed |
| CN-101045936-B | Process of preparing chiral fatty alcohol with acid anhydride as acry radical donor | UNIV JILIN | 2010-06-23 | — | — | CN | claimed |
| CN-101045936-A | Process of preparing chiral fatty alcohol with acid anhydride as acry radical donor | UNIV JILIN (CN) | 2007-10-03 | — | — | CN | claimed |
| US-20050154216-A1 | Novel enantiomeric compounds for treatment of cardiac arrhythmias and methods of use | ARYX THERAPEUTICS | 2005-07-14 | — | — | US | claimed |
| EP-1040105-A2 | METHODS FOR THE ESTERIFICATION OF ALCOHOLS AND COMPOUNDS USEFUL THEREFOR AS POTENTIAL ANTICANCER AGENTS | EMORY UNIVERSITY (US) | 2000-10-04 | — | — | EP | claimed |
| WO-1999031079-A2 | METHODS FOR THE ESTERIFICATION OF ALCOHOLS AND COMPOUNDS USEFUL THEREFOR AS POTENTIAL ANTICANCER AGENTS | EMORY UNIVERSITY (US) | 1999-06-24 | — | — | WO | claimed |
| CN-119776301-A | Alcohol dehydrogenase, recombinant genetically engineered bacterium and application thereof in asymmetric reduction of potential chiral carbonyl compounds | 杭州文德阶生物科技有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-20240374598-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2024-11-14 | — | — | US | disclosed |
| US-20240218021-A1 | CYCLIN INHIBITORS | CIRCLE PHARMA, INC. | 2024-07-04 | — | — | US | disclosed |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-01-25 | — | — | US | disclosed |
| WO-1987004438-A1 | NOVEL OPTICALLY ACTIVE ALKALI METAL MONO- AND DIORGANYLBOROHYDRIDES AND BORANES AND PROCESS FOR PREPARING AND USING SAME | ALDRICH-BORANES, INC. (US) | 1987-07-30 | — | — | WO | disclosed |
| US-4658043-A | Ethers of pantolactone | ROUSSEL UCLAF (FR) | 1987-04-14 | — | — | US | disclosed |
| US-4540797-A | Process for resolution of chiral alcohols or phenols or chiral lactonic compounds | ROUSSEL UCLAF (FR) | 1985-09-10 | — | — | US | disclosed |
| US-4374257-A | Novel ethers containing a lactone group and a chiral atom | ROUSSEL UCLAF (FR) | 1983-02-15 | — | — | US | disclosed |
| US-4265817-A | Novel chiral ethers and their use in resolution of alcohols and phenols | ROUSSEL UCLAF (FR) | 1981-05-05 | — | — | US | disclosed |