SCHEMBL4181087

SCHEMBL4181087

CN(C(=O)c1ccccc1)c1cccc(C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 1/20 0.57
HTT P42858 1/20 0.53
HSD17B2 P37059 5/20 0.53
HSD17B1 P14061 4/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MAOA P21397 2/20 0.51
KDM1A O60341 1/20 0.51
MAOB P27338 1/20 0.51
ATM Q13315 1/20 0.50
NR1H3 Q13133 2/20 0.49
NR1H2 P55055 1/20 0.49
EGFR P00533 1/20 0.49
ERBB2 P04626 1/20 0.49
PLAU P00749 1/20 0.48
KMO O15229 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9001629 0.91 KMT2A (0.62) KMT2AKDM4EHTTHSD17B2HSD17B1
SCHEMBL32688152 0.89 KDM1A (0.58) KMT2AKDM4EHTTHSD17B2L3MBTL1
SCHEMBL493114 0.85 KMT2A (0.75) KMT2AKDM4EHTTMAOAKDM1A
SCHEMBL18780858 0.84 KMT2A (0.56) KMT2AKDM4EHTTHSD17B2HSD17B1
SCHEMBL29940968 0.84 HSD17B2 (0.72) KMT2AKDM4EHTTHSD17B2HSD17B1
SCHEMBL10212283 0.84 HSD17B2 (0.72) KMT2AKDM4EHTTHSD17B2HSD17B1
SCHEMBL9229295 0.84 CA12 (0.47) KMT2AKDM4EL3MBTL1KMO
SCHEMBL9567794 0.83 KMT2A (0.68) KMT2AKDM4EHTTMAOAATM
SCHEMBL9001650 0.83 MAOA (0.63) KMT2AKDM4EHTTHSD17B2L3MBTL1
SCHEMBL1195954 0.83 KMT2A (0.54) KMT2AKDM4EHTTHSD17B2HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090099204-A1 Amide derivative, insecticide containing the same and method for application thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2009-04-16 US disclosed
US-20090099204-A1 Amide derivative, insecticide containing the same and method for application thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2009-04-16 US disclosed
US-20090099204-A1 Amide derivative, insecticide containing the same and method for application thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2009-04-16 US disclosed
CN-101203485-A Amide derivative, pesticide containing such compound and use thereof MITSUI CHEMICALS INC (JP) 2008-06-18 CN disclosed
EP-1916236-A1 AMIDE DERIVATIVE, PESTICIDE CONTAINING SUCH COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2008-04-30 EP disclosed
EP-1916236-A1 AMIDE DERIVATIVE, PESTICIDE CONTAINING SUCH COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2008-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099204-A1 Amide derivative, insecticide containing the same and method for application thereof as insecticide CYP2E1, GSTA1, CYP2S1 KMT2A 499/4885KDM4E 1117/4885HTT 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.