Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024702 | 0.92 | CNR1 (0.48) | CNR1TP53RXFP1PDE4BCASP1 | |
| SCHEMBL4022727 | 0.89 | CHRNA7 (0.42) | TP53RXFP1CASP1CASP7 | |
| SCHEMBL4020761 | 0.88 | CNR1 (0.45) | CNR1TP53RXFP1PDE4BCASP1 | |
| SCHEMBL4191527 | 0.88 | CNR1 (0.53) | CNR1 | |
| SCHEMBL4022474 | 0.87 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL4020217 | 0.86 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4184513 | 0.83 | CNR1 (0.49) | CNR1 | |
| SCHEMBL4026409 | 0.82 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL4020673 | 0.82 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL4192532 | 0.81 | CNR1 (0.46) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095752-A1 | FUSED PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-08-06 | — | — | WO | disclosed |