Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181240 | 0.92 | CNR1 (0.49) | CNR1PDE4BTP53RXFP1CASP1 | |
| SCHEMBL4020761 | 0.91 | CNR1 (0.45) | CNR1PDE4BTP53RXFP1CASP1 | |
| SCHEMBL4020673 | 0.90 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL4021209 | 0.85 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL4027019 | 0.84 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL4192532 | 0.84 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL4024237 | 0.84 | KDM4E (0.48) | CNR1ALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL4017677 | 0.83 | CNR1 (0.44) | CNR1RXFP1CASP1CASP7ALDH1A1 | |
| SCHEMBL4020767 | 0.82 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL4027308 | 0.81 | CNR1 (0.45) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095752-A1 | FUSED PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-08-06 | — | — | WO | disclosed |