Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558983 | 0.89 | RPA1 (0.50) | CNR1CNR2RPA1 | |
| SCHEMBL4021209 | 0.88 | CNR1 (0.47) | CNR1CNR2GABRA2GABRB2 | |
| SCHEMBL4027019 | 0.88 | CNR1 (0.46) | CNR1CNR2GABRA2GABRB2 | |
| SCHEMBL4024237 | 0.87 | KDM4E (0.48) | CNR1CNR2GABRA2GABRB2 | |
| SCHEMBL4186987 | 0.87 | CNR2 (0.46) | CNR1CNR2RPA1 | |
| SCHEMBL4024702 | 0.84 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL4181240 | 0.81 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4017898 | 0.80 | RPA1 (0.46) | CNR1CNR2RPA1 | |
| SCHEMBL4020761 | 0.78 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL4022727 | 0.78 | CHRNA7 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095752-A1 | FUSED PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-08-06 | — | — | WO | disclosed |