Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 11/20 | 0.68 |
| ▸ | CA2 | P00918 | 11/20 | 0.68 |
| ▸ | CA9 | Q16790 | 11/20 | 0.68 |
| ▸ | CA12 | O43570 | 10/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.58 |
| ▸ | CA5A | P35218 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023027 | 0.82 | TSHR (0.64) | CA1CA2CA9CA12PRMT1 | |
| SCHEMBL14628032 | 0.82 | CYP3A4 (1.00) | CYP3A4CA1CA2CA9CA12 | |
| SCHEMBL4773010 | 0.81 | CA1 (1.00) | CYP3A4CA1CA2CA9CA12 | |
| SCHEMBL20522284 | 0.81 | ALDH1A1 (0.70) | CA1CA2CA9CYP2D6MMP1 | |
| SCHEMBL2563975 | 0.81 | CYP3A4 (0.70) | CYP3A4CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL28522062 | 0.81 | CYP3A4 (0.96) | CYP3A4CA1CA2CA9CA12 | |
| SCHEMBL1504601 | 0.81 | ALDH1A1 (0.66) | CYP3A4CA2CA9CA12LMNA | |
| SCHEMBL26212905 | 0.80 | ALDH1A1 (0.53) | CYP3A4CA1CA2CA9CA12 | |
| SCHEMBL8881270 | 0.80 | ALDH1A1 (0.68) | CA1CA2LMNATSHR | |
| SCHEMBL10833147 | 0.79 | CA1 (0.71) | CYP3A4CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048269-A1 | CHEMICAL COMPOUNDS-821 | ASTRAZENECA AB (SE) | 2009-02-19 | — | — | US | disclosed |
| US-4677199-A | Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| EP-0119441-B1 | REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS | BASF Aktiengesellschaft (DE) | 1987-02-25 | — | — | EP | disclosed |
| EP-0119441-A2 | Reactive dyes with substituted 4-fluoropyridaz-6-one groups | BASF Aktiengesellschaft (DE) | 1984-09-26 | — | — | EP | disclosed |
| US-4208324-A | Disperse diaminopyridine-3-azo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4068085-A | YELLOW AND RED ON POLYESTERS AND ACRYLICS | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4066637-A | BASIC DIAMINOPYRIDINE-(3)-AZO DYESTUFFS | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048269-A1 | CHEMICAL COMPOUNDS-821 | TGFBR1, TGFBR2, SMAD3 | CYP3A4 2028/4885CA1 870/4885CA2 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.