Sugi Predict

Sugi Predict / Compounds / SCHEMBL418274

SCHEMBL418274

SCHEMBL418274

CC(=O)Oc1ccc(O)c(C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 2/20 0.56
▸ LMNA P02545 3/20 0.55
▸ CYP3A4 P08684 2/20 0.53
▸ KDM4E B2RXH2 6/20 0.50
▸ GAA P10253 4/20 0.50
▸ GLA P06280 3/20 0.50
▸ ALDH1A1 P00352 1/20 0.49
▸ MAPT P10636 3/20 0.46
▸ TP53 P04637 3/20 0.46
▸ HTT P42858 2/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ POLB P06746 3/20 0.46
▸ PKM P14618 1/20 0.46
▸ TDP1 Q9NUW8 2/20 0.45
▸ CA12 O43570 2/20 0.45
▸ CA9 Q16790 2/20 0.45
▸ KMT2A Q03164 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ TTR P02766 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6823622 0.94 ACHE (0.51) ACHELMNACYP3A4KDM4EGAA
SCHEMBL6823620 0.94 ACHE (0.51) ACHELMNACYP3A4KDM4EGAA
SCHEMBL1490220 0.88 ACHE (0.46) ACHELMNACYP3A4KDM4EGAA
SCHEMBL12332900 0.85 HSD17B10 (0.54) ACHELMNACYP3A4KDM4EGAA
SCHEMBL5682633 0.84 ACHE (0.61) ACHELMNACYP3A4KDM4EGAA
SCHEMBL50809 0.83 CYP3A4 (0.62) ACHELMNACYP3A4KDM4EGAA
SCHEMBL862851 0.83 ACHE (0.65) ACHELMNACYP3A4KDM4EGAA
SCHEMBL28670923 0.83 ELANE (0.53) ACHEKDM4EGAAALDH1A1MAPT
SCHEMBL17242112 0.82 MEN1 (0.53) ACHEMAPTTP53POLBTDP1
SCHEMBL15388793 0.82 ELANE (0.49) ACHELMNACYP3A4KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210188758-A1 PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS VTVX HOLDINGS II LLC 2021-06-24 — — US disclosed
US-10947180-B2 Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists VTV THERAPEUTICS LLC (US) 2021-03-16 — — US disclosed
US-20200215073-A1 PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS HIGH POINT PHARMACEUTICALS, LLC 2020-07-09 — — US disclosed
EP-3670741-A1 WATER-DISPERSIBLE SHEET Nippon Paper Papylia Co., Ltd. (JP) 2020-06-24 — — EP disclosed
US-10471066-B2 Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists VTV THERAPEUTICS LLC (US) 2019-11-12 — — US disclosed
CN-106004143-B Transparent thermal recording medium 理光感热技术（无锡）有限公司 2018-09-21 — — CN disclosed
CN-104553433-B Thermal recording medium 理光感热技术（无锡）有限公司 2018-08-03 — — CN disclosed
US-9929348-B2 Organic semiconductor composition comprising organic semiconductor material and polymer compound FUJIFILM CORPORATION (JP) 2018-03-27 — — US disclosed
US-20180071304-A1 Phenoxy Acetic Acids and Phenyl Propionic Acids as PPAR Delta Agonists HIGH POINT PHARMACEUTICALS, LLC 2018-03-15 — — US disclosed
CN-107635786-A Can laser labelling material and file 爱克发-格法特公司 2018-01-26 — — CN disclosed
CN-1372557-A Neurotrophin production/secretion promoting agent TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-10-02 — — CN disclosed
WO-2002070457-A1 INHIBITOR OF MONOAMINE UPTAKE ELI LILLY AND COMPANY (US) 2002-09-12 — — WO disclosed
EP-0891974-B1 Process for producing chromans KURARAY CO (JP) 2002-04-17 — — EP disclosed
US-6133471-A Process for producing chromans KURARAY CO., LTD. (JP) 2000-10-17 — — US disclosed
US-6130341-A Process for producing chromans KURARAY CO., LTD. (JP) 2000-10-10 — — US disclosed
CN-1235141-A Process for preparing organic compound MITSUI CHEMICALS INC (JP) 1999-11-17 — — CN disclosed
EP-0891974-A1 Process for producing chromans KURARAY CO., LTD. (JP) 1999-01-20 — — EP disclosed
EP-0113042-B1 3,4-DIHYDRO-2H-BENZOPYRAN DERIVATIVES, A METHOD OF PRODUCING THEM, A METHOD OF USING THEM AS STABILIZERS FOR ORGANIC MATERIALS, AND ORGANIC COMPOSITIONS CONTAINING SUCH STABILIZERS KURARAY CO., LTD. (JP) 1989-08-30 — — EP disclosed
US-4523024-A STABILIZERS FOR ORGANIC MATERIALS SENSITIVE TO HEAT, LIGHT, AND/OR OXIDATIVE FACTORS KURARAY CO., LTD. (JP) 1985-06-11 — — US disclosed
EP-0113042-A2 3,4-Dihydro-2H-benzopyran derivatives, a method of producing them, a method of using them as stabilizers for organic materials, and organic compositions containing such stabilizers KURARAY CO., LTD. (JP) 1984-07-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10471066-B2 Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists PPARG, PPARA, PPARD ACHE 3295/4885LMNA 3168/4885CYP3A4 995/4885
US-10947180-B2 Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists PPARG, PPARA, PPARD ACHE 3295/4885LMNA 3168/4885CYP3A4 995/4885
US-20180071304-A1 Phenoxy Acetic Acids and Phenyl Propionic Acids as PPAR Delta Agonists PPARG, PPARA, PPARD ACHE 3295/4885LMNA 3168/4885CYP3A4 995/4885
US-20200215073-A1 PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS PPARG, PPARA, PPARD ACHE 3295/4885LMNA 3168/4885CYP3A4 995/4885
US-20210188758-A1 PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS PPARG, PPARA, PPARD ACHE 3295/4885LMNA 3168/4885CYP3A4 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.