SCHEMBL418279

SCHEMBL418279

CCCCCCCCCCC[CH]C(CC)CCCCC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.38
DNM1 Q05193 4/20 0.37
FAAH O00519 2/20 0.37
TRPV1 Q8NER1 1/20 0.37
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36
ADH4 P08319 1/20 0.36
ADH7 P40394 1/20 0.36
THRB P10828 1/20 0.36
OPRM1 P35372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27946898 1.00 TSHR (0.46) TSHRSMN1; SMN2LMNADNM1FAAH
SCHEMBL9777447 1.00 TSHR (0.46) TSHRSMN1; SMN2LMNADNM1FAAH
SCHEMBL10529071 1.00 TSHR (0.46) TSHRSMN1; SMN2LMNADNM1FAAH
SCHEMBL28099997 1.00 TSHR (0.46) TSHRSMN1; SMN2LMNADNM1FAAH
SCHEMBL16097748 1.00 TSHR (0.46) TSHRSMN1; SMN2LMNADNM1FAAH
SCHEMBL10600803 0.98 TSHR (0.48) TSHRSMN1; SMN2LMNADNM1FAAH
SCHEMBL4053772 0.95 TSHR (0.52) TSHRSMN1; SMN2DNM1FAAHTRPV1
SCHEMBL1978740 0.95 TSHR (0.52) TSHRSMN1; SMN2DNM1FAAHTRPV1
SCHEMBL7501921 0.95 TSHR (0.52) TSHRSMN1; SMN2DNM1FAAHTRPV1
SCHEMBL6892024 0.95 TSHR (0.52) TSHRSMN1; SMN2DNM1FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150118272-A1 METHODS FOR ENHANCING COSMETIC OR DERMATOLOGICAL NOVEL COSMETIC OR DERMATOLOGICAL COMPOSITIONS CONTAINING A DIBENZOYL METHANE DERIVATIVE BY THE ADDITION OF MODIFIED TITANIUM DIOXIDE PARTICLES DSM IP ASSETS B.V. (NL) 2015-04-30 US disclosed
EP-2121611-B1 UV-filter compounds based on alpha,beta-dihydroxyketones DSM IP ASSETS BV (NL) 2015-04-15 EP disclosed
US-8765967-B2 Microcapsules with UV filter activity and process for producing them DSM IP ASSETS B.V. (NE) 2014-07-01 US disclosed
EP-1959914-B1 COSMETIC OR DERMATOLOGICAL COMPOSITIONS COMPRISING MODIFIED TITANIUM DIOXIDE PARTICLES DSM IP ASSETS BV (NL) 2014-05-21 EP disclosed
US-8680147-B2 Compositions DSM IP ASSETS B.V. (NL) 2014-03-25 US disclosed
EP-1885769-B1 NOVEL POLYSILOXANE SUNSCREENS DSM IP ASSETS BV (NL) 2013-08-28 EP disclosed
US-20120294916-A1 NOVEL COSMETIC OR DERMATOLOGICAL COMBINATIONS COMPRISING MODIFIED TITANIUM DIOXIDE PARTICLES DSM IP ASSETS B.V. (NL) 2012-11-22 US disclosed
US-8278459-B2 UV-filter compounds DSM IP ASSETS B.V. (NL) 2012-10-02 US disclosed
EP-1899015-B1 COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT DSM IP ASSETS BV (NL) 2012-03-21 EP disclosed
EP-1722863-B1 MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM DSM IP ASSETS BV (NL) 2012-02-08 EP disclosed
WO-2006128614-A1 NOVEL POLYSILOXANE SUNSCREENS DSM IP ASSETS B.V. (NL) 2006-12-07 WO disclosed
EP-1722863-A1 MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM DSM IP Assets B.V. (NL) 2006-11-22 EP disclosed
WO-2006100018-A1 POLYSILOXANE COATED METAL OXIDE PARTICLES DSM IP ASSETS B.V. (NL) 2006-09-28 WO disclosed
WO-2006099952-A2 CHROMOPHORE COATED METAL OXIDE PARTICLES DSM IP ASSETS B.V. (NL) 2006-09-28 WO disclosed
EP-1474098-B1 SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES DSM IP ASSETS BV (NL) 2006-08-02 EP disclosed
US-20060073106-A1 Novel stabilized cinnamic ester sunscreen compositions DSM IP ASSETS B.V. (NL) 2006-04-06 US disclosed
EP-1589940-A1 NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS DSM IP Assets B.V. (NL) 2005-11-02 EP disclosed
WO-2005053631-A1 MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM DSM IP ASSETS B.V. (NL) 2005-06-16 WO disclosed
US-20050019278-A1 Sunscreen compositions as well as dihydropyridines and dihydropyranes ROCHE VITAMINS AG (CH) 2005-01-27 US disclosed
WO-2004069216-A1 NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS DSM IP ASSETS B.V. (CH) 2004-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060073106-A1 Novel stabilized cinnamic ester sunscreen compositions SUN2, NISCH, BCAS2 TSHR 4849/4885SMN1; SMN2 3390/4885LMNA 1146/4885
US-20050019278-A1 Sunscreen compositions as well as dihydropyridines and dihydropyranes DHPS, DSG1, DHODH TSHR 4639/4885SMN1; SMN2 4037/4885LMNA 2067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.