Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 13/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 13/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 13/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 13/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 13/20 | 0.58 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285731 | 0.90 | HDAC3 (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5319421 | 0.83 | HDAC3 (0.80) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5319525 | 0.83 | HDAC2 (0.67) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28919064 | 0.77 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydroxyamine SCHEMBL6418576 | 0.76 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5318872 | 0.76 | HDAC3 (0.79) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28919033 | 0.76 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5335863 | 0.75 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4179056 | 0.75 | HDAC3 (0.77) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4308115 | 0.74 | HDAC2 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089598-A2 | MSMB-GENE METHYLATION BASED DIAGNOSIS, STAGING AND PROGNOSIS OF PROSTATE CANCER | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2009-07-23 | — | — | WO | disclosed |