SCHEMBL4183426

SCHEMBL4183426

COC(=O)Cc1ccc(Br)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.61
ALDH1A1 P00352 4/20 0.61
GFER P55789 1/20 0.61
HSP90AB1 P08238 1/20 0.53
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
KDM4E B2RXH2 2/20 0.48
KMT2A Q03164 1/20 0.48
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
TSHR P16473 3/20 0.46
HPGD P15428 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MAPT P10636 3/20 0.46
TP53 P04637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
YWHAG P61981 1/20 0.45
CCR6 P51684 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
ABL1 P00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1303490 0.86 ALDH1A1 (0.66) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL30027871 0.86 ALDH1A1 (0.66) GAAALDH1A1GFERHSP90AB1CYP4F2
Bromide SCHEMBL8459768 0.85 ALDH1A1 (0.64) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL3668882 0.84 GAA (0.72) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL29446278 0.84 GAA (0.72) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL4190020 0.83 APP (0.50) GAAALDH1A1GFERCCR6HKDC1
SCHEMBL14712149 0.83 ALDH1A1 (0.53) GAAALDH1A1GFERHSP90AB1CYP4F2
Methyl Alcohol SCHEMBL27946196 0.82 GAA (0.70) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL7500705 0.81 ALDH1A1 (0.51) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL31236975 0.81 ABL1 (0.56) GAAALDH1A1GFERHSP90AB1CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727537-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF Adaxion Therapeutics, Inc. (US) 2026-04-22 EP disclosed
US-20250064941-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF ADAXION THERAPEUTICS, INC. 2025-02-27 US disclosed
WO-2024259007-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF OSPREY BIOPHARMACEUTICALS, INC. (US) 2024-12-19 WO disclosed
WO-2021011873-A1 BORON-CONTAINING RHO KINASE INHIBITORS PERCIPIAD, INC. (US) 2021-01-21 WO disclosed
US-20090192203-A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2009-07-30 US disclosed
US-20090192203-A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2009-07-30 US disclosed
US-20090192203-A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2009-07-30 US disclosed
US-20080292608-A1 Compounds and Compositions as Ppar Modulators IRM LLC (BM) 2008-11-27 US disclosed
US-20080292608-A1 Compounds and Compositions as Ppar Modulators IRM LLC (BM) 2008-11-27 US disclosed
US-20080292608-A1 Compounds and Compositions as Ppar Modulators IRM LLC (BM) 2008-11-27 US disclosed
EP-1945620-A2 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2008-07-23 EP disclosed
EP-1945633-A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2008-07-23 EP disclosed
WO-2007056366-A2 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2007-05-18 WO disclosed
WO-2007056497-A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2007-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250064941-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF SIGLEC7, SIGLEC9, CD2BP2 GAA 525/4885ALDH1A1 802/4885GFER 615/4885
US-20080292608-A1 Compounds and Compositions as Ppar Modulators PPARG, PPARA, PPARD GAA 995/4885ALDH1A1 1696/4885GFER 2993/4885
US-20090192203-A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS PPARG, PPARA, PPARD GAA 995/4885ALDH1A1 1696/4885GFER 2993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.