Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | GFER | P55789 | 1/20 | 0.72 |
| ▸ | YWHAG | P61981 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29446278 | 1.00 | GAA (0.72) | GAAALDH1A1GFERYWHAGMAPT | |
| Methyl Alcohol SCHEMBL27946196 | 0.98 | GAA (0.70) | GAAALDH1A1GFERYWHAGMAPT | |
| SCHEMBL14768426 | 0.87 | GAA (0.70) | GAAALDH1A1GFERYWHAGMAPT | |
| SCHEMBL334348 | 0.85 | GAA (0.63) | GAAALDH1A1GFERYWHAGMAPT | |
| SCHEMBL30096935 | 0.85 | GAA (0.68) | GAAALDH1A1GFERYWHAGMAPT | |
| SCHEMBL2127019 | 0.85 | GAA (0.68) | GAAALDH1A1GFERYWHAGMAPT | |
| SCHEMBL8145260 | 0.85 | ALDH1A1 (0.68) | GAAALDH1A1GFERYWHAGMAPT | |
| SCHEMBL8146212 | 0.85 | GAA (0.63) | GAAALDH1A1GFERYWHAGMAPT | |
| SCHEMBL14531746 | 0.84 | GAA (0.61) | GAAALDH1A1GFERYWHAGMAPT | |
| SCHEMBL2981679 | 0.84 | GAA (0.61) | GAAALDH1A1GFERYWHAGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388369-A | Polyphenol modified polyurethane chain extender, photo-thermal polyurethane material, and preparation methods and applications thereof | 北京化工大学 | 2024-07-26 | — | — | CN | claimed |
| CN-110128246-B | Preparation method of hydroxytyrosol | 杭州志源生物科技有限公司 | 2022-07-26 | — | — | CN | claimed |
| CN-112447316-A | Halogen-free flame-retardant insulated wire and halogen-free flame-retardant cable | 日立金属株式会社 | 2021-03-05 | — | — | CN | claimed |
| CN-110128246-A | A kind of preparation method of hydroxytyrosol | 杭州志源生物科技有限公司 | 2019-08-16 | — | — | CN | claimed |
| CN-101497567-B | Preparation of caffeic acid 3,4-dihydroxyphenyl ethyl ester and its derivative phenyl acrylic acid phenyl alkyl ester compound | ZHIZHEN ZHANG | 2012-07-25 | — | — | CN | claimed |
| CN-101497567-A | Preparation of 3-(3,4-dihydroxyphenyl)-acrylic acid 2-(3,4-dihydroxyphenyl)-ethyl ester and derivative phenyl acrylic acid phenyl alkyl ester compound | ZHIZHEN ZHANG (CN) | 2009-08-05 | — | — | CN | claimed |
| WO-2007009590-A1 | PROCESS FOR THE PREPARATION OF PHENOLIC COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2007-01-25 | — | — | WO | claimed |
| US-7125986-B2 | Penicillanic acid derivative compounds and methods of making | SOUTHERN METHODIST UNIVERSITY FOUNDATION FOR RESEARCH (US) | 2006-10-24 | — | — | US | claimed |
| US-20040220399-A1 | Penicillanic acid derivative compounds and methods of making | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2004-11-04 | — | — | US | claimed |
| US-20030216372-A1 | Inhibitors of serine and metallo-beta-lactamases | ALAMX L.L.C. | 2003-11-20 | — | — | US | claimed |
| JP-2002542249-A | — | — | 2002-12-10 | — | — | JP | claimed |
| US-6436398-B2 | ADMINISTERING A BETA-LACTAM ANTIBIOTIC WITH A BETA-LACTAMASE INHIBITING COMPOUND SUCH AS BENZHYDRYL 2-BETA-(CHLOROACETOXY-METHYL)-6-((Z)-(TERT-BUTOXYCARBONYL)METHYLENE) PENICILLINATE TO TREAT BETA-LACTAM RESISTANT BACTERIAL INFECTIONS | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-08-20 | — | — | US | claimed |
| US-6407091-B1 | CEPHALOSPORIN DERIVATIVES; TREATING MICROBIAL AND ANTIBIOTIC RESISTANCE | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-06-18 | — | — | US | claimed |
| EP-0966471-B1 | 2-BETA-SUBSTITUTED-6-ALKYLIDENE PENICILLANIC ACID DERIVATIVES AS BETA-LACTAMASE INHIBITORS | RES CORP TECHNOLOGIES INC (US) | 2002-06-12 | — | — | EP | claimed |
| EP-1169323-A1 | BETA-LACTAMASE INHIBITING COMPOUNDS | Research Corporation Technologies, Inc (US) | 2002-01-09 | — | — | EP | claimed |
| US-20010021706-A1 | 2 beta-substituted-6-alkylidene penicillanic acid derivatives as beta-lactamase inhibitors | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2001-09-13 | — | — | US | claimed |
| US-6156745-A | 2β-substituted-6-alkylidene penicillanic acid derivatives as β-lactamase inhibitors | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-12-05 | — | — | US | claimed |
| WO-2000063213-A1 | BETA-LACTAMASE INHIBITING COMPOUNDS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-10-26 | — | — | WO | claimed |
| EP-0966471-A1 | 2-BETA-SUBSTITUTED-6-ALKYLIDENE PENICILLANIC ACID DERIVATIVES AS BETA-LACTAMASE INHIBITORS | Research Corporation Technologies, Inc (US) | 1999-12-29 | — | — | EP | claimed |
| WO-1999033838-A1 | 2-β-SUBSTITUTED-6-ALKYLIDENE PENICILLANIC ACID DERIVATIVES AS β-LACTAMASE INHIBITORS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-07-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220399-A1 | Penicillanic acid derivative compounds and methods of making | MRPL21, CYP51A1, RPIA | GAA 135/4885ALDH1A1 79/4885GFER 752/4885 |
| US-20030216372-A1 | Inhibitors of serine and metallo-beta-lactamases | SRR, BACE1, PRSS1 | GAA 93/4885ALDH1A1 471/4885GFER 361/4885 |
| US-20010021706-A1 | 2 beta-substituted-6-alkylidene penicillanic acid derivatives as beta-lactamase inhibitors | IDUA, NAALAD2, GLA | GAA 36/4885ALDH1A1 88/4885GFER 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.