SCHEMBL418405

SCHEMBL418405

O=C=NCCSCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1096758 0.83 TRPA1 (0.32)
SCHEMBL2760845 0.82
SCHEMBL2567111 0.82
SCHEMBL3780469 0.82
SCHEMBL3778781 0.82
SCHEMBL3777063 0.82
SCHEMBL3777062 0.82
SCHEMBL2761447 0.80
SCHEMBL7723019 0.80 LMNA (0.33)
SCHEMBL2760869 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344562-B1 FLUOROPOLYMER COMPOSITIONS AND TREATED SUBSTRATES CHEMOURS CO FC LLC (US) 2019-05-22 EP disclosed
EP-2215098-B1 FLUOROALKYL SILANES DU PONT (US) 2014-08-20 EP disclosed
EP-2662354-A2 Sulfur containing fluoroalkyl amines and isocyanates E. I. du Pont de Nemours and Company (US) 2013-11-13 EP disclosed
EP-2215056-B1 SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES DU PONT (US) 2013-10-30 EP disclosed
US-8501952-B2 Fluoroalkyl silanes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-08-06 US disclosed
US-8420826-B2 Fluoroalkyl silanes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-04-16 US disclosed
US-8324314-B2 Fluoropolymer compositions and treated substrates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-12-04 US disclosed
US-8153846-B2 Sulfur containing fluoroalkyl amines and isocyanates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-04-10 US disclosed
US-20120022266-A1 FLUOROALKYL SILANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-26 US disclosed
US-20120022267-A1 FLUOROALKYL SILANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-26 US disclosed
US-8058463-B2 Fluorosilanes E. I. DU PONT DE NEMOURS AND COMPNAY (US) 2011-11-15 US disclosed
US-20110084227-A1 FLUOROPOLYMER COMPOSITIONS AND TREATED SUBSTRATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-04-14 US disclosed
US-20090143608-A1 SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES E. I. DU PONT DE NEMOURS AND COMPNAY 2009-06-04 US disclosed
US-20090143598-A1 FLUOROSILANES E.I. DU PONT DE NEMOURS AND COMPANY 2009-06-04 US disclosed