Diphenylmethanol

Diphenylmethanol

SCHEMBL4184366

OC(O)(Cc1ccccc1)c1ccccc1.OC(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
KCNA5 P22460 1/20 0.41
TRPA1 O75762 1/20 0.41
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
FDPS P14324 1/20 0.39
HIF1A Q16665 2/20 0.38
CYP3A4 P08684 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 1/20 0.37
KIF11 P52732 2/20 0.36
SLC6A2 P23975 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9987352 0.89 CYP1A2 (0.52) CYP1A2CYP2C9CYP2C19KCNA5TRPA1
SCHEMBL1698191 0.86 CYP2C9 (0.67) CYP1A2CYP2C9CYP2C19KCNA5TRPA1
Ammonia Solution, Strong SCHEMBL8959000 0.84 CYP2C9 (0.64) CYP1A2CYP2C9CYP2C19KCNA5TRPA1
Triphenylmethanol SCHEMBL16601082 0.76 SMN1; SMN2 (0.47) CYP2C9KCNA5LMNAMAPK1SMN1; SMN2
SCHEMBL7019811 0.73 MEN1 (0.51) CYP1A2CYP2C9CYP2C19LMNAMAPK1
SCHEMBL7020533 0.73 CYP19A1 (0.56) CYP1A2CYP2C9CYP2C19LMNAMAPK1
Diphenylmethanol SCHEMBL10868602 0.72 SMN1; SMN2 (0.61) LMNAKDM4EMAPK1SMN1; SMN2HIF1A
Diphenylmethanol SCHEMBL41571 0.72 SMN1; SMN2 (0.61) LMNAKDM4EMAPK1SMN1; SMN2HIF1A
Diphenylmethanol SCHEMBL11564700 0.72 SMN1; SMN2 (0.61) LMNAKDM4EMAPK1SMN1; SMN2HIF1A
Diphenylmethanol SCHEMBL6434457 0.72 SMN1; SMN2 (0.61) LMNAKDM4EMAPK1SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264212-B1 ELEMENTS FOR FORMING PRINT-OUT IMAGES DU PONT (US) 2009-02-18 EP disclosed
EP-1264212-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. du Pont de Nemours and Company (US) 2002-12-11 EP disclosed
US-20020146649-A1 Elements for forming print-out images E. I. DU PONT DE NEMOURS AND COMPANY 2002-10-10 US disclosed
WO-2001067175-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-13 WO disclosed