Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8959000

N.OC(O)(Cc1ccccc1)c1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.64
CYP2C19 P33261 3/20 0.64
CYP1A2 P05177 3/20 0.64
KCNA5 P22460 1/20 0.48
FDPS P14324 1/20 0.47
TSHR P16473 1/20 0.46
HIF1A Q16665 2/20 0.44
CYP3A4 P08684 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
SLC6A2 P23975 2/20 0.43
TAAR1 Q96RJ0 1/20 0.43
LMNA P02545 2/20 0.42
MAPK1 P28482 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP2D6 P10635 2/20 0.41
KIF11 P52732 2/20 0.41
MAPT P10636 1/20 0.40
RECQL P46063 1/20 0.40
TRPA1 O75762 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1698191 0.98 CYP2C9 (0.67) CYP2C9CYP2C19CYP1A2KCNA5FDPS
Diphenylmethanol SCHEMBL4184366 0.84 CYP1A2 (0.52) CYP2C9CYP2C19CYP1A2KCNA5FDPS
SCHEMBL9987352 0.84 CYP1A2 (0.52) CYP2C9CYP2C19CYP1A2KCNA5FDPS
SCHEMBL7019811 0.83 MEN1 (0.51) CYP2C9CYP2C19CYP1A2FDPSSMN1; SMN2
SCHEMBL7020533 0.83 CYP19A1 (0.56) CYP2C9CYP2C19CYP1A2FDPSTSHR
SCHEMBL28446237 0.79 CYP1A2 (0.50) CYP2C9CYP2C19CYP1A2KCNA5FDPS
SCHEMBL7025430 0.78 LTA4H (0.53) CYP2C9CYP2C19CYP1A2SMN1; SMN2LMNA
SCHEMBL912792 0.78 CYP2C9 (0.67) CYP2C9CYP2C19CYP1A2KCNA5FDPS
SCHEMBL2854811 0.78 CYP2C9 (0.67) CYP2C9CYP2C19CYP1A2KCNA5FDPS
SCHEMBL28624141 0.78 CYP2C9 (1.00) CYP2C9CYP2C19CYP1A2KCNA5FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8208599-A None JP disclosed
JP-H08208599-A PROSTAGLANDIN DERIVATIVE TAISHO PHARMACEUT CO LTD 1996-08-13 JP disclosed