Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176725 | 0.79 | KMT2A (0.41) | PTGS1PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL4190168 | 0.77 | KDM4E (0.42) | PTGS1PTGS2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5180770 | 0.74 | KDM4E (0.34) | PTGS1PTGS2KDM4EGAA | |
| SCHEMBL5180767 | 0.74 | KDM4E (0.34) | PTGS1PTGS2KDM4EGAA | |
| SCHEMBL7971125 | 0.61 | KDM4E (0.47) | IDO1ALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL27986571 | 0.61 | TDP1 (0.46) | PTGS1PTGS2IDO1ALDH1A1CYP1A2 | |
| SCHEMBL2050250 | 0.57 | IDO1 (0.57) | IDO1ALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL5544435 | 0.57 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2410450 | 0.57 | TRAP1 (0.50) | IDO1ALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL18612923 | 0.55 | IDO1 (0.55) | IDO1ALDH1A1CYP1A2CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018183-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2009-01-15 | — | — | US | claimed |
| US-7442807-B2 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2008-10-28 | — | — | US | claimed |
| US-7442807-B2 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2008-10-28 | — | — | US | disclosed |
| US-7186748-B2 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2007-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018183-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | MC1R, MC5R, MC3R | PTGS1 1289/4885PTGS2 2082/4885IDO1 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.