⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386139 | 0.86 | — | — | |
| SCHEMBL28060372 | 0.76 | — | — | |
| SCHEMBL30269988 | 0.75 | KEAP1 (0.46) | — | |
| SCHEMBL28365458 | 0.75 | KEAP1 (0.46) | — | |
| SCHEMBL1861414 | 0.75 | ALDH1A1 (0.49) | — | |
| SCHEMBL9821780 | 0.74 | — | — | |
| SCHEMBL28868986 | 0.74 | — | — | |
| SCHEMBL173628 | 0.74 | F2 (0.46) | — | |
| SCHEMBL28173602 | 0.74 | — | — | |
| SCHEMBL9324320 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503457-B2 | Fluorine-containing pyrimidine compound, and method for producing same | UNIMATEC CO., LTD. (JP) | 2025-12-23 | — | — | US | disclosed |
| US-20250250257-A1 | NOVEL CRYSTALLINE FORMS | ASSEMBLY BIOSCIENCES, INC. (US) | 2025-08-07 | — | — | US | disclosed |
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2025-03-13 | — | — | US | disclosed |
| CN-119421877-A | Substituted heterocyclic compounds as HSET inhibitors | 默克专利股份公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4463444-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2024-11-20 | — | — | EP | disclosed |
| CN-118339163-A | Novel crystalline forms | 组装生物科学股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117186072-A | Compound for inhibiting phosphatidylinositol-3-kinase gamma subtype activity and preparation method and application thereof | 安驰达生物医药技术(广州)有限公司 | 2023-12-08 | — | — | CN | disclosed |
| US-20230295096-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES INC (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230295096-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES INC (US) | 2023-09-21 | — | — | US | disclosed |
| EP-3150592-B1 | ALK KINASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | SHANGHAI EMERALD WELLCARES PHARMACEUTICAL CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |
| US-8273784-B2 | Dinitropyrazole derivatives, their preparation, and energetic compositions comprising them | HERAKLES (FR) | 2012-09-25 | — | — | US | disclosed |
| US-7935699-B2 | Pyrazole glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2011-05-03 | — | — | US | disclosed |
| US-7718374-B2 | Single nucleotide polymorphism analysis of highly polymorphic target sequences | ELITECH HOLDING B.V. (NL) | 2010-05-18 | — | — | US | disclosed |
| US-20090186931-A1 | Dinitropyrazole derivatives, their preparation, and energetic compositions comprising them | ARIANEGROUP SAS (FR) | 2009-07-23 | — | — | US | disclosed |
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2009-04-16 | — | — | US | disclosed |
| US-20090087922-A1 | SINGLE NUCLEOTIDE POLYMORPHISM ANALYSIS OF HIGHLY POLYMORPHIC TARGET SEQUENCES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-02 | — | — | US | disclosed |
| US-7348146-B2 | Single nucleotide polymorphism analysis of highly polymorphic target sequences | EPOCH BIOSCIENCES, INC. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20080021032-A1 | Pyrazole glucokinase activators | BERTHEL STEVEN JOSEPH | 2008-01-24 | — | — | US | disclosed |
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |