Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 3/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184690 | 1.00 | ERCC1 (0.46) | ERCC1ERCC4TBXA2RPTGFRPTGER3 | |
| SCHEMBL4184695 | 1.00 | ERCC1 (0.46) | ERCC1ERCC4TBXA2RPTGFRPTGER3 | |
| SCHEMBL4175198 | 0.87 | ERCC1 (0.45) | ERCC1ERCC4MEN1KMT2ACA12 | |
| SCHEMBL4175188 | 0.87 | ERCC1 (0.45) | ERCC1ERCC4MEN1KMT2ACA12 | |
| SCHEMBL4175195 | 0.87 | ERCC1 (0.45) | ERCC1ERCC4MEN1KMT2ACA12 | |
| SCHEMBL4186111 | 0.84 | ALDH1A1 (0.42) | ERCC1ERCC4TBXA2RPTGFRPTGER3 | |
| SCHEMBL4186118 | 0.84 | ALDH1A1 (0.42) | ERCC1ERCC4TBXA2RPTGFRPTGER3 | |
| SCHEMBL4186115 | 0.84 | ALDH1A1 (0.42) | ERCC1ERCC4TBXA2RPTGFRPTGER3 | |
| SCHEMBL4188837 | 0.84 | MEN1 (0.43) | MEN1KMT2AMAPTL3MBTL1SENP1 | |
| SCHEMBL4188845 | 0.84 | MEN1 (0.43) | MEN1KMT2AMAPTL3MBTL1SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090191193-A1 | Aryl Vinyl Sulfides, Sulfones, Sulfoxides and Sulfonamides, Derivatives Thereof and Therapeutic Uses Thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090191193-A1 | Aryl Vinyl Sulfides, Sulfones, Sulfoxides and Sulfonamides, Derivatives Thereof and Therapeutic Uses Thereof | ARSA, STS, SULT2A1 | ERCC1 3371/4885ERCC4 3746/4885TBXA2R 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.