SCHEMBL4184754

SCHEMBL4184754

O=C(C(F)(F)F)C(F)(F)Cl

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
CA2 P00918 1/20 0.33
CES2 O00748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1962768 0.85 ALDH1A1 (0.38) ALDH1A1TP53TSHRCA2
Water SCHEMBL31522142 0.81 ALDH1A1 (0.35) ALDH1A1TP53TSHR
Water SCHEMBL411670 0.81 ALDH1A1 (0.35) ALDH1A1TP53TSHR
SCHEMBL2275880 0.79 ALDH1A1 (0.41) ALDH1A1TP53TSHRCA2CES2
SCHEMBL688151 0.79 ALDH1A1 (0.33) ALDH1A1TP53TSHR
SCHEMBL4209214 0.79 ALDH1A1 (0.33) ALDH1A1TP53TSHRCA2CES2
SCHEMBL5861894 0.79 ALDH1A1 (0.41) ALDH1A1TP53TSHRCA2
SCHEMBL344 0.76 CA2 (0.41) ALDH1A1CA2CES2
SCHEMBL27892503 0.76 CA2 (0.41) ALDH1A1CA2CES2
Water SCHEMBL8828341 0.76 ALDH1A1 (0.32) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160133-A Preparation method of allyl fluorine-containing (methyl) acrylate 杭州宝明新材料科技有限公司 2022-10-11 CN claimed
US-20090139232-A1 Ambient Temperature Energy Generating System COLLIS MATTHEW P 2009-06-04 US claimed
EP-0483850-B1 Process for producing salts of fluorinated alcohols AUSIMONT SPA (IT) 1995-08-09 EP claimed
US-5227539-A PROCESS FOR PRODUCING SALTS OF FLUORINATED ALCOHOLS AUSIMONT S.P.A. (IT) 1993-07-13 US claimed
EP-0483850-A2 Process for producing salts of fluorinated alcohols AUSIMONT S.p.A. (IT) 1992-05-06 EP claimed
US-4599455-A Process of purifying fluorinated carbonyl compound mixed with hydrogen fluoride CENTRAL GLASS COMPANY, LIMITED NO. 5253 OAZA OKIUBE, UBE CITY, YAMAGUCHI PREFECTURE, JAPAN (JP) 1986-07-08 US claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
CN-115160133-A Preparation method of allyl fluorine-containing (methyl) acrylate 杭州宝明新材料科技有限公司 2022-10-11 CN disclosed
CN-110770200-B Process for preparing polyfluorinated allyl ethers and compounds related thereto 3M创新有限公司 2022-10-04 CN disclosed
CN-115043794-A Preparation method of allyl fluorine-containing glycidyl ether 杭州宝明新材料科技有限公司 2022-09-13 CN disclosed
US-11292763-B2 Methods of making a polyfluorinated allyl ether and compounds relating to the methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
EP-3896052-A1 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M Innovative Properties Co. (US) 2021-10-20 EP disclosed
EP-3625201-B1 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M INNOVATIVE PROPERTIES CO (US) 2021-09-29 EP disclosed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US disclosed
US-4041229-A Polymeric fluoromethylated dienes HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-08-09 US disclosed
US-4004073-A Polymeric fluoromethylated dienes HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-01-18 US disclosed
US-3985723-A Trifluoroacetylation process THE UNIVERSITY OF MISSISSIPPI (US) 1976-10-12 US disclosed
US-3978030-A Polymers of fluorinated dioxoles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-31 US disclosed
US-3962460-A Ether compounds as inhalant anesthetics AIRCO, INC. (US) 1976-06-08 US disclosed
US-3949112-A Treatment of fibrous materials with polymers and copolymers of fluoromethylated dienes HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-04-06 US disclosed