SCHEMBL4185113

SCHEMBL4185113

C=C(C)C(=O)OCCOc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
LMNA P02545 1/20 0.46
TDP1 Q9NUW8 3/20 0.41
POLB P06746 3/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
IGF2BP2 Q9Y6M1 1/20 0.35
MAOB P27338 6/20 0.34
PDE3B Q13370 1/20 0.34
PDE3A Q14432 1/20 0.34
P2RY12 Q9H244 1/20 0.34
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29315604 0.94 TDP1 (0.48) NPC1RAB9ALMNATDP1POLB
SCHEMBL4188814 0.94 TDP1 (0.46) NPC1RAB9ALMNATDP1POLB
SCHEMBL29315607 0.94 TDP1 (0.50) NPC1RAB9ALMNATDP1POLB
SCHEMBL11376140 0.91 POLB (0.41) NPC1RAB9ALMNATDP1POLB
SCHEMBL8614784 0.89 NPC1 (0.45) NPC1RAB9ALMNATDP1POLB
SCHEMBL29315615 0.86 NPC1 (0.46) NPC1RAB9ALMNATDP1POLB
SCHEMBL93485 0.85 NPC1 (0.47) NPC1RAB9ALMNATDP1POLB
SCHEMBL29358846 0.85 NPC1 (0.47) NPC1RAB9ALMNATDP1POLB
SCHEMBL9417137 0.85 RAB9A (0.43) NPC1RAB9ALMNATDP1POLB
SCHEMBL19328389 0.85 POLB (0.50) TDP1POLBAPEX1HTTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3124525-B1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE TEIJIN LTD (JP) 2020-11-04 EP disclosed
US-9758630-B2 Polymer substrate with hard coat layer and manufacturing method for such polymer substrate TEIJIN LIMITED (JP) 2017-09-12 US disclosed
US-20170107345-A1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE TEIJIN LIMITED (JP) 2017-04-20 US disclosed
EP-3124525-A1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE Teijin Limited (JP) 2017-02-01 EP disclosed
EP-1995056-B1 MULTILAYER BODY TEIJIN CHEMICALS LTD (JP) 2016-08-17 EP disclosed
US-20160054840-A1 TOUCH SENSOR WITH FRONT PANEL ASAHI GLASS COMPANY, LIMITED (JP) 2016-02-25 US disclosed
EP-1516722-B1 ACRYLIC RESIN COMPOSITION, ORGANOSILOXANE RESIN COMPOSITION AND LAMINATES MADE BY USING THEM TEIJIN CHEMICALS LTD (JP) 2015-09-02 EP disclosed
US-8859099-B2 Laminate of an acrylic resin composition layer containing triazine based ultra-violet compounds and an organosiloxane resin composition layer TEIJIN CHEMICALS, LTD. (JP) 2014-10-14 US disclosed
US-8765891-B2 Laminate of an acrylic resin composition layer containing triazine based ultra-violet compounds and an organosiloxane resin composition layer TEIJIN CHEMICALS, LTD. (JP) 2014-07-01 US disclosed
US-20130164543-A1 FRONT PANEL FOR TOUCH SENSOR ASAHI GLASS COMPANY, LIMITED (JP) 2013-06-27 US disclosed
EP-1995056-A1 MULTILAYER BODY Teijin Chemicals, Ltd. (JP) 2008-11-26 EP disclosed
EP-1164005-B1 SURFACE-PROTECTED TRANSPARENT PLASTIC COMPOSITE TEIJIN CHEMICALS LTD (JP) 2008-07-23 EP disclosed
US-7070859-B2 Acrylic resin composition organosiloxane resin composition and laminate comprising the same TEIJIN CHEMICALS, LTD. (JP) 2006-07-04 US disclosed
EP-1516722-A1 ACRYLIC RESIN COMPOSITION, ORGANOSILOXANE RESIN COMPOSITION AND LAMINATES MADE BY USING THEM Teijin Chemicals, Ltd. (JP) 2005-03-23 EP disclosed
US-6846567-B1 Surface-protected transparent plastic composite TEIJIN CHEMICALS, LTD. (JP) 2005-01-25 US disclosed
US-20040247878-A1 Acrylic resin composition organosiloxane resin composition and laminate comprising the same TEIJIN CHEMICALS LTD. (JP) 2004-12-09 US disclosed
EP-0899091-B1 Transparent coated molded product and method for producing the same ASAHI GLASS CO LTD (JP) 2003-10-29 EP disclosed
US-6383641-B1 CURED INTERIOR LAYER FROM POLYFUNCTIONAL COMPOUND; EXTERIOR SILICA COATING CURED FROM POLYSILAZANE; WEAR RESISTANCE, WEATHERPROOF ASAHI GLASS COMPANY LTD. (JP) 2002-05-07 US disclosed
EP-1164005-A1 SURFACE-PROTECTED TRANSPARENT PLASTIC COMPOSITE Teijin Chemicals, Ltd. (JP) 2001-12-19 EP disclosed
EP-0899091-A2 Transparent coated molded product and method for producing the same Asahi Glass Company Ltd. (JP) 1999-03-03 EP disclosed