Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185113 | 0.89 | NPC1 (0.46) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL7268063 | 0.87 | NPC1 (0.46) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL4445465 | 0.84 | NPC1 (0.49) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL4188814 | 0.84 | TDP1 (0.46) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL29315604 | 0.84 | TDP1 (0.48) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL26489368 | 0.84 | NPC1 (0.48) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL29613654 | 0.84 | NPC1 (0.35) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL373843 | 0.84 | NPC1 (0.35) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL29315607 | 0.83 | TDP1 (0.50) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL28735972 | 0.82 | POLB (0.39) | NPC1RAB9ALMNATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714134-A | SUNSCREEN AGENTS | SOCIETE L'OREAL S.A. (FR) | 1998-02-03 | — | — | US | disclosed |
| US-5610257-A | SUNSCREENS | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |