SCHEMBL418521

SCHEMBL418521

N[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](N)C[C@H]2N)O[C@H](CO)[C@H]1O

nearest known ligand 0.90

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 2/20 0.90
▸ KDM4E B2RXH2 1/20 0.90
▸ TSHR P16473 2/20 0.79
▸ GJA1 P17302 1/20 0.79
▸ GJB2 P29033 1/20 0.79
▸ MEN1 O00255 1/20 0.79
▸ CYP2C9 P11712 1/20 0.79
▸ KMT2A Q03164 1/20 0.79
▸ ALDH1A1 P00352 1/20 0.79
▸ HPSE Q9Y251 1/20 0.71
▸ CYP3A4 P08684 1/20 0.71
▸ MAPT P10636 1/20 0.70
▸ LMNA P02545 1/20 0.69
▸ HSD17B10 Q99714 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14922823 1.00 ALOX15 (0.90) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL19917387 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL12535725 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL13018550 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL17265214 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL23879718 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL14944403 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL16174041 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL9250504 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2
Bekanamycin SCHEMBL12553422 0.95 ALOX15 (1.00) ALOX15KDM4ETSHRGJA1GJB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10203334-B2 Methods and compositions related to nucleic acid binding assays Nubad, LLC (US) 2019-02-12 — — US claimed
US-20160282357-A1 METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID BINDING ASSAYS Nubad, LLC 2016-09-29 — — US claimed
US-9017943-B2 Methods and compositions related to nucleic acid binding assays NUBAD LLC (US) 2015-04-28 — — US claimed
US-20140330001-A1 METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID BINDING ASSAYS Nubad, LLC (US) 2014-11-06 — — US claimed
WO-2008005276-A2 GROWTH FACTOR DELIVERY SYSTEM CONTAINING ANTIMICROBIAL AGENTS DIRECTCONTACT LLC (US) 2008-01-10 — — WO claimed
WO-2000040692-A9 METHODS AND COMPOSITIONS FOR DELIVERING NUCLEIC ACIDS VALENTIS INC (US) 2001-06-07 — — WO claimed
WO-2000040692-A2 METHODS AND COMPOSITIONS FOR DELIVERING NUCLEIC ACIDS VALENTIS, INC. (US) 2000-07-13 — — WO claimed
US-5900406-A Use of antibiotics of the type 2-deoxystreptamine substituted with aminosugars to inhibit growth of microorganisms containing group I introns NZYM, INC. (US) 1999-05-04 — — US claimed
CN-1106401-A Novel macrolides and the use thereof CIBA GEIGY AG (CH) 1995-08-09 — — CN claimed
EP-0445563-B1 Use of an antibacterial and deodorant processing agent MEIJI SEIKA KAISHA (JP) 1995-05-24 — — EP claimed
US-5268168-A Shiff base SAKAI ENGINEERING CO., LTD. (JP) 1993-12-07 — — US claimed
US-5229132-A Simultaneous administration of coated and uncoated drug forms, improved treatment of stomach and intestines GRIMBERG GEORGES SERGE (FR) 1993-07-20 — — US claimed
EP-0445563-A2 Use of an antibacterial and deodorant processing agent MEIJI SEIKA KAISHA LTD. (JP) 1991-09-11 — — EP claimed
US-4297485-A Production of a selectively protected N-acylated derivative of an aminoglycosidic antibiotic ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1981-10-27 — — US claimed
US-4136254-A PROCESS OF SELECTIVELY BLOCKING AMINO FUNCTIONS IN AMINOGLYCOSIDES USING TRANSITION METAL SALTS AND INTERMEDIATES USED THEREBY SCHERING CORPORATION (US) 1979-01-23 — — US claimed
US-4120955-A BACTERICIDES ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1978-10-17 — — US claimed
US-3965089-A Process for the production of a cyclic ureido-derivative of a deoxystreptamine-containing antibiotic and products thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) 1976-06-22 — — US claimed
JP-53046940-A — — None — — JP disclosed
US-3965089-A Process for the production of a cyclic ureido-derivative of a deoxystreptamine-containing antibiotic and products thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) 1976-06-22 — — US disclosed
US-3939043-A CULTURING STREPTOMYCES HOFUENSIS ABBOTT LABORATORIES (US) 1976-02-17 — — US disclosed
Send feedback