Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185323 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4185315 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4176474 | 0.94 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4176471 | 0.94 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4176478 | 0.94 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4175730 | 0.89 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4175733 | 0.89 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4175736 | 0.89 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4188795 | 0.88 | KMT2A (0.49) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL4188791 | 0.88 | KMT2A (0.49) | CYP1A2CYP3A4CYP2C9ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090191193-A1 | Aryl Vinyl Sulfides, Sulfones, Sulfoxides and Sulfonamides, Derivatives Thereof and Therapeutic Uses Thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090191193-A1 | Aryl Vinyl Sulfides, Sulfones, Sulfoxides and Sulfonamides, Derivatives Thereof and Therapeutic Uses Thereof | ARSA, STS, SULT2A1 | CYP1A2 1062/4885CYP3A4 2311/4885CYP2C9 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.