Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | PRKDC | P78527 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553602 | 0.94 | ALDH1A1 (0.68) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL27118585 | 0.90 | ALDH1A1 (0.66) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL3942989 | 0.89 | ALDH1A1 (0.64) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL28629055 | 0.87 | ALDH1A1 (0.77) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL18953087 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL2559051 | 0.86 | MAPT (0.71) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL5926044 | 0.86 | MAPT (0.63) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL2557444 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL14439519 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL7307761 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP3A4KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180339985-A1 | PDD COMPOUNDS | FEMTOGENIX LIMITED (GB) | 2018-11-29 | — | — | US | disclosed |
| US-9150899-B2 | Identification of compounds modifying a cellular response | 2CUREX (DK) | 2015-10-06 | — | — | US | disclosed |
| US-20150104427-A1 | ENZYME-ASSISTED SPATIAL DECORATION OF BIOMATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-04-16 | — | — | US | disclosed |
| WO-2013071126-A1 | ENZYME-ASSISTED SPATIAL DECORATION OF BIOMATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-16 | — | — | WO | disclosed |
| US-20130123140-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2013-05-16 | — | — | US | disclosed |
| EP-1888619-B1 | Compounds modifying apoptosis | 2CUREX APS (DK) | 2013-04-17 | — | — | EP | disclosed |
| US-8318717-B2 | Tetrapeptide capable of inhibiting binding of the Smac protein to Inhibitors of apoptosis, thus promoting apoptosis or sensitizing cells; antiproliferative and anticarcinogenic agents | 2CUREX (DK) | 2012-11-27 | — | — | US | disclosed |
| US-20090239755-A1 | Identification of Compounds Modifying A Cellular Response | 2CUREX (DK) | 2009-09-24 | — | — | US | disclosed |
| EP-1759212-B1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2008-12-17 | — | — | EP | disclosed |
| US-20080194537-A1 | Compounds Modifying Apoptosis | 2CUREX (DK) | 2008-08-14 | — | — | US | disclosed |
| EP-1888619-A2 | COMPOUNDS MODIFYING APOPTOSIS | 2cureX ApS (DK) | 2008-02-20 | — | — | EP | disclosed |
| EP-1759212-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | Carlsberg A/S (DK) | 2007-03-07 | — | — | EP | disclosed |
| WO-2007009457-A2 | IDENTIFICATION OF PROTEIN LIGANDS MODIFYING A CELLULAR RESPONSE | 2CUREX APS (DK) | 2007-01-25 | — | — | WO | disclosed |
| WO-2006128455-A2 | COMPOUNDS MODIFYING APOPTOSIS | 2CUREX APS (DK) | 2006-12-07 | — | — | WO | disclosed |
| WO-2005116656-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194537-A1 | Compounds Modifying Apoptosis | API5, BAX, BAD | ALDH1A1 3642/4885MAPT 2819/4885CYP3A4 4747/4885 |
| US-20090239755-A1 | Identification of Compounds Modifying A Cellular Response | MCL1, PMAIP1, CDC37 | ALDH1A1 4225/4885MAPT 3385/4885CYP3A4 2873/4885 |
| US-20180339985-A1 | PDD COMPOUNDS | DRD1, DRD3, DRD2 | ALDH1A1 2727/4885MAPT 3926/4885CYP3A4 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.