Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 19/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ERG | P11308 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 6/20 | 0.36 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822498 | 0.89 | TACR3 (0.39) | TACR3KCNH2ERGCYP1A2CYP2C9 | |
| SCHEMBL3817030 | 0.88 | TACR3 (0.40) | TACR3KCNH2ERGCYP1A2CYP2C9 | |
| SCHEMBL3819604 | 0.87 | TACR3 (0.36) | TACR3KCNH2ERGTACR2TACR1 | |
| SCHEMBL3810556 | 0.85 | TACR3 (0.43) | TACR3KCNH2ERGCYP1A2CYP2C9 | |
| SCHEMBL3429230 | 0.83 | ALDH1A1 (0.51) | — | |
| SCHEMBL3815823 | 0.83 | TACR3 (0.42) | TACR3KCNH2ERGCYP1A2CYP2C9 | |
| SCHEMBL3819870 | 0.82 | TACR3 (0.43) | TACR3KCNH2ERGCYP1A2CYP2C9 | |
| SCHEMBL3811664 | 0.82 | TACR3 (0.43) | TACR3KCNH2ERGCYP1A2CYP2C9 | |
| SCHEMBL3815789 | 0.82 | TACR3 (0.51) | TACR3KCNH2ERGCYP1A2CYP2C9 | |
| SCHEMBL3813972 | 0.81 | ALDH1A1 (0.36) | TACR3TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |