Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.71 |
| ▸ | RELA | Q04206 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | RARA | P10276 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371650 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9734086 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9733644 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9744977 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL8534144 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL5687511 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9817507 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| Hydrochloric Acid SCHEMBL9323786 | 0.99 | RARB (0.97) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| Hydrochloric Acid SCHEMBL9744777 | 0.99 | RARB (0.97) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| Hydrochloric Acid SCHEMBL9746644 | 0.99 | RARB (0.97) | RARBRAB9ASMN1; SMN2NPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | claimed |
| JP-4247076-A | — | — | None | — | — | JP | disclosed |
| JP-4266876-A | — | — | None | — | — | JP | disclosed |
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | SONY CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1907347-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | Arcadia Pharmaceuticals Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009083-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| US-5389290-A | Ferroelectric liquid crystalline materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0440134-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5217644-A | MESOMORPHIC COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING SAME, LIQUID CRYSTAL DEVICE USING SAME AND DISPLAY APPARATUS | CANON KABUSHIKI KAISHA (JP) | 1993-06-08 | — | — | US | disclosed |
| US-5167857-A | Optically active, optical modulation | CANON KABUSHIKI KAISHA (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0258430-A1 | NEMATIC LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987005316-A1 | NEMATIC LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-09-11 | — | — | WO | disclosed |
| EP-0227717-A1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS. | MERCK PATENT GMBH (DE) | 1987-07-08 | — | — | EP | disclosed |
| EP-0220297-A1 | NITROGEN-CONTAINING HETEROCYCLES. | MERCK PATENT GMBH (DE) | 1987-05-06 | — | — | EP | disclosed |
| EP-0220254-A1 | BENZONITRILES. | MERCK PATENT GMBH (DE) | 1987-05-06 | — | — | EP | disclosed |
| WO-1986007055-A1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-12-04 | — | — | WO | disclosed |
| WO-1986006372-A1 | BENZONITRILE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-11-06 | — | — | WO | disclosed |
| WO-1986006373-A1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-11-06 | — | — | WO | disclosed |
| EP-0175591-A2 | Lactic acid derivative, liquid crystal composition containing same and liquid crystal device | CANON KABUSHIKI KAISHA (JP) | 1986-03-26 | — | — | EP | disclosed |
| US-4460770-A | Liquid crystal mixture | HOFFMANN-LA ROCHE INC. (US) | 1984-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | RARB, RARA, RARG | RARB 1/4885RAB9A 103/4885SMN1; SMN2 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.