Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.71 |
| ▸ | RELA | Q04206 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | RARA | P10276 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371650 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL4186000 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9734086 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9733644 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9744977 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL8534144 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9817507 | 1.00 | RARB (1.00) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| Hydrochloric Acid SCHEMBL9323786 | 0.99 | RARB (0.97) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| Hydrochloric Acid SCHEMBL9744777 | 0.99 | RARB (0.97) | RARBRAB9ASMN1; SMN2NPC1NFKB1 | |
| Hydrochloric Acid SCHEMBL9746644 | 0.99 | RARB (0.97) | RARBRAB9ASMN1; SMN2NPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130172558-A1 | NAPROXEN-BASED CHIRAL COMPOUNDS AND LIQUID CRYSTAL DISPLAY APPLICATIONS | CITIZEN FINETECH MIYOTA CO., LTD. (JP) | 2013-07-04 | — | — | US | disclosed |
| EP-1375627-B1 | Optically active compound and liquid crystal composition containing the same | MITSUBISHI GAS CHEMICAL CO (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6699532-B2 | CHIRAL DOPANT HAVING A HELICAL TWISTING POWER (HTP) OF AT LEAST 50 AND HAVING ITS INDUCED HELICAL PITCH DECREASING IN LENGTH WITH AN INCREASE IN TEMPERATURE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20040007691-A1 | OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-01-15 | — | — | US | disclosed |
| EP-1375627-A1 | Optically active compound and liquid crystal composition containing the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-01-02 | — | — | EP | disclosed |
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| US-5759443-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1998-06-02 | — | — | US | disclosed |
| EP-0440061-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1998-04-01 | — | — | EP | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |
| EP-0315193-B1 | Optically active compound and chiral liquid crystal composition containing the same | NIPPON TELEGRAPH & TELEPHONE (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0409234-B1 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | CHISSO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-5284599-A | Benzothiazole with alkyl group having asymmetric carbon connected to halogen; improved response | CANON KABUSHIKI KAISHA (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5236619-A | Benzothiazoles | CANON KABUSHIKI KAISHA (JP) | 1993-08-17 | — | — | US | disclosed |
| US-5164112-A | Optical activity, ferroelectric, short response times | CHISSO CORPORATION (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5059345-A | Spontaneous polarization in wide temperature range and high speed response | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0440061-A1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0409234-A2 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | Chisso Corporation (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0315193-A2 | Optically active compound and chiral liquid crystal composition containing the same | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1989-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172558-A1 | NAPROXEN-BASED CHIRAL COMPOUNDS AND LIQUID CRYSTAL DISPLAY APPLICATIONS | CRY1, CRY2, ALOX5 | RARB 2088/4885RAB9A 4828/4885SMN1; SMN2 3451/4885 |
| US-20040007691-A1 | OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE COMPOUND | TOP1, ROCK1, SFRP1 | RARB 2038/4885RAB9A 417/4885SMN1; SMN2 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.