Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.66 |
| ▸ | GAA | P10253 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 5/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 5/20 | 0.65 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.64 |
| ▸ | MPI | P34949 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17541734 | 0.79 | GFER (1.00) | ALDH1A1GAAKDM4EHPGDAPOBEC3G | |
| SCHEMBL7996480 | 0.67 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EHPGDAPOBEC3G | |
| SCHEMBL7622866 | 0.64 | MAPK1 (0.47) | ALDH1A1KDM4EHPGDGFERRAB9A | |
| SCHEMBL24317550 | 0.64 | NPC1 (0.47) | ALDH1A1GAAKDM4EHPGDPKM | |
| SCHEMBL15029205 | 0.62 | MAPK1 (0.42) | ALDH1A1GAAKDM4EPKMRAB9A | |
| SCHEMBL15007066 | 0.62 | NR1H2 (0.64) | ALDH1A1HPGDRAB9ASMN1; SMN2LMNA | |
| SCHEMBL11838228 | 0.62 | KDM4E (0.50) | ALDH1A1GAAKDM4EHPGDPKM | |
| SCHEMBL12562793 | 0.61 | BCL2L1 (0.55) | RAB9ASMN1; SMN2POLB | |
| SCHEMBL10337645 | 0.61 | BCL2L1 (0.55) | RAB9ASMN1; SMN2POLB | |
| SCHEMBL197346 | 0.61 | BCL2L1 (0.55) | RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009087218-A1 | THIAZOLTRIAZOLES AND THIAZOLIMIDAZOLES AS ANTAGONISTS OF THE MGLUR5 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2009-07-16 | — | — | WO | disclosed |