Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186745 | 1.00 | FKBP1A (0.46) | FKBP1AALDH1A1 | |
| SCHEMBL6883802 | 0.88 | FKBP1A (0.47) | FKBP1A | |
| SCHEMBL5497946 | 0.88 | FKBP1A (0.47) | FKBP1A | |
| SCHEMBL5492839 | 0.88 | FKBP1A (0.47) | FKBP1A | |
| SCHEMBL4189488 | 0.87 | FKBP1A (0.56) | FKBP1AALDH1A1 | |
| SCHEMBL4186372 | 0.87 | FKBP1A (0.56) | FKBP1AALDH1A1 | |
| SCHEMBL468859 | 0.86 | FKBP1A (0.47) | FKBP1AALDH1A1 | |
| SCHEMBL468860 | 0.86 | FKBP1A (0.47) | FKBP1AALDH1A1 | |
| SCHEMBL27262313 | 0.84 | FKBP1A (0.44) | FKBP1AALDH1A1 | |
| SCHEMBL7048968 | 0.83 | ACE (0.50) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1865953-A4 | COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF | YU RUEY J (US) | 2008-04-30 | — | — | EP | claimed |
| EP-1865953-A2 | COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF | Yu, Ruey J., Dr. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006101940-A2 | COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF | YU, RUEY, J. (US) | 2006-09-28 | — | — | WO | claimed |
| US-20060211754-A1 | Compositions comprising N-propanoyl derivatives of amino acids, aminocarbohydrates and derivatives thereof | YU RUEY J | 2006-09-21 | — | — | US | claimed |
| US-9586991-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-8716236-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20130172264-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20090186853-A1 | COMPOSITIONS COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF | YU RUEY J | 2009-07-23 | — | — | US | disclosed |
| EP-1865953-A4 | COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF | YU RUEY J (US) | 2008-04-30 | — | — | EP | disclosed |
| EP-1865953-A2 | COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF | Yu, Ruey J., Dr. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006101940-A2 | COMPOSITION COMPRISING N-PROPANOYL DERIVATIVES OF AMINO ACIDS, AMINOCARBOHYDRATES AND DERIVATIVES THEREOF | YU, RUEY, J. (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20060211754-A1 | Compositions comprising N-propanoyl derivatives of amino acids, aminocarbohydrates and derivatives thereof | YU RUEY J | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172264-A1 | INHIBITORS OF IAP | BIRC5, XIAP, BIRC3 | FKBP1A 1562/4885ALDH1A1 3819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.