SCHEMBL4186908

SCHEMBL4186908

C=CCCCCC(C)[Si](Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.33
USP2 O75604 2/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.31
ABCC4 O15439 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4958552 0.85 TSHR (0.38) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL3878685 0.84 TSHR (0.33) TSHRALDH1A1
SCHEMBL4960214 0.77 TSHR (0.38) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL153874 0.75 TSHR (0.37) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL4958703 0.75 TSHR (0.37) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL11063317 0.75
SCHEMBL8437291 0.74 TSHR (0.39) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL1760678 0.74
SCHEMBL31351425 0.74 TSHR (0.35) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL31351432 0.74 ALDH1A1 (0.37) TSHRALDH1A1MAPTUSP2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
EP-0637902-A1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC. (US) 1995-02-08 EP claimed
US-20230111586-A1 CONSUMABLE FOR ANALYTE DETECTION ALIGHT SCIENCES INC. 2023-04-13 US disclosed
CN-115920796-A Functionalized surfaces and preparation thereof 特韦斯特生物科学公司 2023-04-07 CN disclosed
US-9909986-B2 Thickness determination and layer characterization using terahertz scanning reflectometry APPLIED RESEARCH AND PHOTONICS, INC. (US) 2018-03-06 US disclosed
US-20150316475-A1 THICKNESS DETERMINATION AND LAYER CHARACTERIZATION USING TERAHERTZ SCANNING REFLECTOMETRY APPLIED RES AND PHOTONICS INC (US) 2015-11-05 US disclosed
EP-1037511-B1 Surface treatment of copper to prevent microcracking in flexible circuits JX NIPPON MINING & METALS CORP (JP) 2012-07-18 EP disclosed
US-7575781-B2 Applying polymer coating to substrate by performing a bake-out cycle with a chemical vapor deposition system and performing a deposition cycle with the chemical vapor deposition system; enhances adherence of the polymeric materials to the surface of the substrate; coating medical equipment, stents SUR MODICS, INC. (US) 2009-08-18 US disclosed
US-20090169857-A1 HIGHLY POROUS LAYERS MADE OF MOF MATERIALS AND METHOD FOR PRODUCING SUCH LAYERS SUD-CHEMIE AG (DE) 2009-07-02 US disclosed
US-20090130735-A1 Static Support Bed for Purification, Separation, Detection, Modification and/or Immobilization of Target Entities and Method of Using Thereof DRO BIOSYSTEMS, S. L. (ES) 2009-05-21 US disclosed
EP-1910533-A2 STATIC SUPPORT BED FOR PURIFICATION, SEPARATION, DETECTION, MODIFICATION AND/OR IMMOBILIZATION OF TARGET ENTITIES AND METHOD USING THEREOF Dro Biosystems, S.L. (ES) 2008-04-16 EP disclosed
EP-1037511-A2 Surface treatment of copper to prevent microcracking in flexible circuits GA-TEK Inc. (US) 2000-09-20 EP disclosed
US-6086743-A Adhesion enhancement for metal foil GOULD ELECTRONICS, INC. (US) 2000-07-11 US disclosed
EP-0974685-A1 Metal foil with improved bonding to substrates and method for making said foil Gould Electronics Inc. (US) 2000-01-26 EP disclosed
US-5908542-A CONTACTING A METAL FOIL WITH AN ACIDIC SOLUTION; PLACING THE METAL FOIL IN A NICKEL TREATMENT BATH AND APPLYING A CURRENT THROUGH THE NICKEL TREATMENT BATH, WHEREIN THE NICKEL TREATMENT BATH CONTAINS AT LEAST ABOUT TWO PLATING ZONES, GOULD ELECTRONICS INC. (US) 1999-06-01 US disclosed
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP disclosed
US-5885436-A Adhesion enhancement for metal foil GOULD ELECTRONICS INC. (US) 1999-03-23 US disclosed
EP-0896502-A1 Method of treating metal foil for enhancing adhesion Gould Electronics Inc. (US) 1999-02-10 EP disclosed
US-5622782-A USEFUL IN MANUFACTURE OF PRINTED CIRCUIT BOARDS GOULD INC. (US) 1997-04-22 US disclosed
EP-0637902-A1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC. (US) 1995-02-08 EP disclosed