SCHEMBL4186922

SCHEMBL4186922

Cc1ccccc1Nc1cc(C(=O)O)c(Nc2ccccc2C)cc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 5/20 0.60
AKR1C2 P52895 4/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
AKR1B10 O60218 2/20 0.60
AKR1B1 P15121 2/20 0.60
AKR1C1 Q04828 2/20 0.60
LMNA P02545 2/20 0.60
CYP1A2 P05177 2/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2C9 P11712 2/20 0.60
PTGS2 P35354 2/20 0.60
HIF1A Q16665 2/20 0.60
TDP1 Q9NUW8 2/20 0.60
TRPA1 O75762 1/20 0.60
ABCB11 O95342 1/20 0.60
DHFR P00374 1/20 0.60
MPO P05164 1/20 0.60
CHRM1 P11229 1/20 0.60
PTGS1 P23219 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27796772 0.98 AKR1C3 (0.58) AKR1C3AKR1C2MEN1KMT2AAKR1B10
SCHEMBL29834970 0.87 AKR1C3 (0.77) AKR1C3AKR1C2MEN1KMT2AAKR1B10
SCHEMBL1186480 0.87 AKR1C3 (0.77) AKR1C3AKR1C2MEN1KMT2AAKR1B10
SCHEMBL3237547 0.85 AKR1C3 (0.66) AKR1C3AKR1C2MEN1KMT2AAKR1B10
Bicarbonate SCHEMBL31082205 0.84 RAB9A (0.61) AKR1C3AKR1C2MEN1KMT2AAKR1B10
SCHEMBL4223433 0.84 FABP4 (0.58) AKR1C3AKR1C2MEN1KMT2AAKR1B10
SCHEMBL11105154 0.82 AKR1C3 (0.66) AKR1C3AKR1C2MEN1KMT2AAKR1B10
Oxalic Acid SCHEMBL31082365 0.82 RAB9A (0.59) AKR1C3AKR1C2MEN1KMT2AAKR1B10
SCHEMBL11581567 0.81 MEN1 (0.59) AKR1C3AKR1C2MEN1KMT2AAKR1B10
SCHEMBL11787456 0.80 AKR1C3 (0.51) AKR1C3AKR1C2MEN1KMT2AAKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284890-B1 CYCLIZING A 2,5-DIARYLAMINO-6,13-DIHYDROTEREPHTHALIC ACID WITH POLYPHOSPHORIC ACID AND TREATING THE MELT WITH SULFURIC ACID; SMALL PARTICLE SIZE CIBA SPECIALTY CHEMICALS CORP. 2001-09-04 US claimed
US-4064129-A Process for making quinacridone and its derivatives HARMON COLORS CORPORATION (US) 1977-12-20 US claimed
US-12577420-B2 Pigment composition, coloring agent, and inkjet ink DIC CORPORATION (JP) 2026-03-17 US disclosed
EP-4450565-A1 PIGMENT COMPOSITION, COLORING AGENT, AND INKJET INK DIC Corporation (JP) 2024-10-23 EP disclosed
US-12104063-B2 Solid solution of quinacridone and ink composition containing same DIC CORPORATION (JP) 2024-10-01 US disclosed
US-20240240039-A1 PIGMENT COMPOSITION, COLORING AGENT, AND INKJET INK DIC CORPORATION (JP) 2024-07-18 US disclosed
WO-2023112375-A1 PIGMENT COMPOSITION, COLORING AGENT, AND INKJET INK DIC株式会社 2023-06-22 WO disclosed
CN-113600112-B Device for preparing 2,5-di (p-toluidinyl) terephthalic acid 河北彩客新材料科技股份有限公司 2023-04-28 CN disclosed
EP-3822321-A1 QUINACRIDONE PIGMENT COMPOSITION, AND INK COMPOSITION HAVING SAME DIC Corporation (JP) 2021-05-19 EP disclosed
EP-3786236-A1 SOLID SOLUTION OF QUINACRIDONE AND INK COMPOSITION CONTAINING SAME DIC Corporation (JP) 2021-03-03 EP disclosed
US-20210040327-A1 SOLID SOLUTION OF QUINACRIDONE AND INK COMPOSITION CONTAINING SAME DIC CORPORATION (JP) 2021-02-11 US disclosed
US-20090186200-A1 2,5-DI(METHOXYANILINO) TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM SUN CHEMICAL CORPORATION 2009-07-23 US disclosed
EP-2024325-A1 2,5-DI(METHOXYANILINO)TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM Sun Chemical Corporation (US) 2009-02-18 EP disclosed
WO-2007139724-A1 2,5-DI(METHOXYANILINO)TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM SUN CHEMICAL CORPORATION (US) 2007-12-06 WO disclosed
EP-1334154-A2 PROCESS FOR MANUFACTURING PIGMENTARY QUINACRIDONES SUN CHEMICAL CORPORATION (US) 2003-08-13 EP disclosed
EP-1031615-B1 Aqueous process for the preparation of linear quinacridones having a reduced particle size CIBA SC HOLDING AG (CH) 2003-07-23 EP disclosed
WO-2002038680-A2 PROCESS FOR MANUFACTURING PIGMENTARY QUINACRIDONES SUN CHEMICAL CORPORATION (US) 2002-05-16 WO disclosed
US-6284890-B1 CYCLIZING A 2,5-DIARYLAMINO-6,13-DIHYDROTEREPHTHALIC ACID WITH POLYPHOSPHORIC ACID AND TREATING THE MELT WITH SULFURIC ACID; SMALL PARTICLE SIZE CIBA SPECIALTY CHEMICALS CORP. 2001-09-04 US disclosed
EP-1031615-A2 Aqueous process for the preparation of linear quinacridones having a reduced particle size Ciba SC Holding AG (CH) 2000-08-30 EP disclosed
US-4018743-A Process for preparing triketoimidazolidines HOECHST AKTIENGESELLSCHAFT (DT) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577420-B2 Pigment composition, coloring agent, and inkjet ink IK, PIR, MKI67 AKR1C3 2614/4885AKR1C2 3477/4885MEN1 331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.