SCHEMBL4187016

SCHEMBL4187016

O=C(CCCC1CCN(C(=O)CCC2CCCCC2)CC1)c1ncco1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4184652 0.99 FAAH (0.98) FAAH
SCHEMBL4185078 0.92 FAAH (1.00) FAAH
SCHEMBL4182618 0.91 FAAH (0.98) FAAH
SCHEMBL12420272 0.88 FAAH (0.78) FAAH
SCHEMBL4177803 0.87 FAAH (1.00) FAAH
SCHEMBL4190828 0.85 FAAH (0.74) FAAH
SCHEMBL4189685 0.85 FAAH (0.98) FAAH
SCHEMBL4193196 0.85 FAAH (0.75) FAAH
SCHEMBL4187409 0.84 FAAH (1.00) FAAH
SCHEMBL4182631 0.83 FAAH (0.77) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090111778-A1 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-30 US claimed
US-20090111778-A1 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-30 US disclosed
US-20090111778-A1 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-30 US disclosed
US-20090111778-A1 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-30 US disclosed
WO-2007061862-A2 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111778-A1 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase FAAH, FAAH2, HCRTR2 FAAH 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.