Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187097 | 0.78 | MAPK1 (0.62) | MAPK1HPGDSCN9ALIPELMNA | |
| SCHEMBL1011905 | 0.76 | MAPK1 (0.69) | MAPK1HPGDSCN9ALIPELMNA | |
| SCHEMBL4198445 | 0.73 | MAPK1 (0.53) | MAPK1HPGDSCN9ALIPETHRB | |
| SCHEMBL1010121 | 0.70 | MAPK1 (0.69) | MAPK1HPGDSCN9ALIPELMNA | |
| SCHEMBL1011777 | 0.69 | MAPK1 (0.51) | MAPK1HPGDSCN9ALIPELMNA | |
| SCHEMBL9255996 | 0.69 | MAPK1 (0.74) | MAPK1HPGDSCN9ALIPELMNA | |
| SCHEMBL8026492 | 0.66 | MAPK1 (0.56) | MAPK1SCN9ALIPELMNATHRB | |
| SCHEMBL5119799 | 0.65 | MAPK1 (0.58) | MAPK1HPGDSCN9ALIPELMNA | |
| SCHEMBL1012147 | 0.65 | MAPK1 (0.61) | MAPK1HPGDSCN9ALIPELMNA | |
| SCHEMBL14810451 | 0.64 | MAPK1 (0.53) | MAPK1HPGDSCN9ALIPELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076508-A2 | BIARYL ETHER UREA COMPOUNDS | Pfizer Products Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008047229-A2 | BIARYL ETHER UREA COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-04-24 | — | — | WO | disclosed |