⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782786 | 0.81 | TP53 (0.42) | — | |
| SCHEMBL10729404 | 0.79 | CA1 (0.32) | — | |
| SCHEMBL8621251 | 0.77 | — | — | |
| SCHEMBL6509468 | 0.77 | — | — | |
| SCHEMBL3524631 | 0.77 | — | — | |
| SCHEMBL27486514 | 0.77 | — | — | |
| SCHEMBL10777854 | 0.76 | TP53 (0.57) | — | |
| SCHEMBL9550819 | 0.75 | LMNA (0.31) | — | |
| SCHEMBL29172890 | 0.75 | CA1 (0.31) | — | |
| SCHEMBL10766852 | 0.74 | TP53 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652621-A | MALEIMIDE WITH SULFONATE OR SULFATE GROUP, DRILLING FLUID DISPERSANT | NIPPON ZEON CO., LTD. (JP) | 1987-03-24 | — | — | US | claimed |
| CN-113543752-B | Multi-dose ocular fluid delivery system | 博士伦爱尔兰有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-117106727-A | Preparation method of CAR-NK cell preparation | 翔鹏佑康(北京)科技有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116568312-A | Stable semi-solid chewable gel compositions and methods of making and using the same | 西雅图咖米公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-113543752-A | Multi-dose ophthalmic fluid delivery system | 科达莱昂治疗公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-112739345-A | PIM kinase inhibitor compositions, methods and uses thereof | 斯奈普生物公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-106687140-A | Use of cysteamine in treating infections caused by yeasts/moulds | 诺瓦生命科学有限公司 | 2017-05-17 | — | — | CN | disclosed |
| WO-2016179398-A1 | ISOFORM-SELECTIVE LYSINE DEACETYLASE INHIBITORS | WASHINGTON UNIVERSITY (US) | 2016-11-10 | — | — | WO | disclosed |
| US-20090209480-A1 | CENTRAL ADMINISTRATION OF STABLE FORMULATIONS OF THERAPEUTIC AGENTS FOR CNS CONDITIONS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-08-20 | — | — | US | disclosed |
| US-4687845-A | INSECTICIDES | FINE ORGANICS LIMITED (GB) | 1987-08-18 | — | — | US | disclosed |
| US-4652621-A | MALEIMIDE WITH SULFONATE OR SULFATE GROUP, DRILLING FLUID DISPERSANT | NIPPON ZEON CO., LTD. (JP) | 1987-03-24 | — | — | US | disclosed |
| EP-0189972-A1 | Preparation of thiazine derivatives | FINE ORGANICS LIMITED (GB) | 1986-08-06 | — | — | EP | disclosed |
| US-4532322-A | Preparation of thiazine derivatives | FINE ORGANICS LIMITED (GB) | 1985-07-30 | — | — | US | disclosed |
| EP-0127413-A2 | Preparation of thiazine derivatives | FINE ORGANICS LIMITED (GB) | 1984-12-05 | — | — | EP | disclosed |
| US-3983048-A | Composition for accelerating oxygen removal comprised of a mixture of aqueous hydrazine and an aryl amine compound | OLIN CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |