SCHEMBL9550819

SCHEMBL9550819

NCC(N)OS(=O)(=O)O.[Pt]

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
SLC6A6 P31641 1/20 0.31
CYP2C19 P33261 1/20 0.31
BLM P54132 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6509468 0.97
SCHEMBL8621251 0.77
SCHEMBL4187588 0.75
SCHEMBL9325436 0.74 CA2 (0.33) LMNASLC6A6CYP2C19BLMCA2
SCHEMBL29275070 0.71 CA1 (0.32) CA2
Ammonia Solution, Strong SCHEMBL16470724 0.71 CA1 (0.32) CA2
SCHEMBL10782786 0.71 TP53 (0.42) CA2
SCHEMBL1343067 0.70
SCHEMBL10337500 0.70
SCHEMBL28618947 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5186940-A Antitumor agents THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-02-16 US disclosed
US-5178876-A Antitumor agents THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-01-12 US disclosed
EP-0248036-B1 HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-06-17 EP disclosed
US-5041581-A Antitumor agents THE UNIVERSITY OF TEXAS SYSTEM BOARD OF REGENTS (US) 1991-08-20 US disclosed
EP-0248036-A1 HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES. UNIV TEXAS (US) 1987-12-09 EP disclosed
WO-1987002364-A1 HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1987-04-23 WO disclosed