SCHEMBL4187792

SCHEMBL4187792

CC(=O)CO[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27428693 0.77
SCHEMBL513709 0.74
SCHEMBL8852902 0.74
SCHEMBL6718384 0.74
SCHEMBL19821442 0.74
SCHEMBL4184491 0.74 ALDH1A1 (0.41)
SCHEMBL1100317 0.73
SCHEMBL1003264 0.72
SCHEMBL2393634 0.72
SCHEMBL2393636 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105832-A Oxalyl-containing aryl sulfide and preparation method and application thereof 青岛康乔药业集团有限公司 2023-11-24 CN claimed
CN-117062800-A Aryl sulfide and preparation method and application thereof 山东康乔生物科技有限公司 2023-11-14 CN claimed
CN-111825585-B Aryl sulfide containing benzylamine structure and synthesis method and application thereof 山东康乔生物科技有限公司 2021-12-14 CN claimed
WO-2021056922-A1 ARYL SULFIDE CONTAINING BENZYLAMINE STRUCTURE, SYNTHESIS METHOD THEREFOR AND APPLICATION THEREOF 山东康乔生物科技有限公司 2021-04-01 WO claimed
CN-111825585-A Aryl sulfide containing benzylamine structure and synthesis method and application thereof 山东康乔生物科技有限公司 2020-10-27 CN claimed
US-RE39072-E1 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same MITSUBISHI PHARMA CORPORATION (JP) 2006-04-18 US claimed
EP-1134222-B1 IMIDAZO[4,5-b]PYRIDINIUMMETHYL-CONTAINING CEPHEM COMPOUNDS HAVING BROAD ANTIBACTERIAL SPECTRUM SHIONOGI & CO (JP) 2005-04-13 EP claimed
EP-1002792-B1 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME MITSUBISHI PHARMA CORP (JP) 2004-07-14 EP claimed
US-6214873-B1 PREVENTION OR SUPPRESION OF REJECTION OF ORGANS OR BONE MARROW TRANSPLANTATION; TREATMENT OF AUTOIMMUNE DISEASES OR ALLERGIC DISEASES; DECREASE IN TOXICITY AND HIGHER SAFETY WELFIDE CORPORATION (JP) 2001-04-10 US claimed
EP-0321186-B1 6-(Substituted methylene)penems BEECHAM GROUP PLC (GB) 1994-03-02 EP claimed
US-4801703-A PHOSPHORUS COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-01-31 US claimed
US-4788185-A Cephalosporin compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-11-29 US claimed
US-4684724-A ANTIBIOTICS, BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-08-04 US claimed
US-4675397-A MICROBIOCIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-06-23 US claimed
US-4665067-A BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-05-12 US claimed
US-4560508-A BETA-LACTAMASE INHIBITORS, ANINICROBIAL AGENT, CHEMICAL INTERMEDIATE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-12-24 US claimed
US-4550105-A BETA-LACTAMASE INHIBITORS, ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-10-29 US claimed
US-4533495-A Method of producing 2-azetidinone-1-sulfonic acid compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-08-06 US claimed
EP-0053387-A1 Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor Takeda Chemical Industries, Ltd. (JP) 1982-06-09 EP claimed
US-4180571-A Arylmalonamido-1-oxadethiacephalosporins SHIONOGI & CO., LTD. (JP) 1979-12-25 US claimed