⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164045 | 0.79 | THRB (0.31) | — | |
| SCHEMBL3098373 | 0.76 | — | — | |
| SCHEMBL9189712 | 0.74 | — | — | |
| SCHEMBL4187792 | 0.74 | — | — | |
| SCHEMBL1387290 | 0.74 | — | — | |
| SCHEMBL6718384 | 0.72 | — | — | |
| SCHEMBL515513 | 0.72 | — | — | |
| SCHEMBL7762375 | 0.72 | — | — | |
| SCHEMBL8852902 | 0.72 | — | — | |
| SCHEMBL3859770 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832082-B1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ASTRAZENECA AB (SE) | 2001-11-21 | — | — | EP | claimed |
| EP-0516392-B1 | Naphthyridine derivatives as angiotensin II inhibitors | ASTRAZENECA AB (SE) | 2001-08-29 | — | — | EP | claimed |
| US-6083951-A | FOR THE TREATMENT OF DISEASES OR MEDICAL CONDITIONS SUCH AS HYPERTENSION, PULMONARY HYPERTENSION, CARDIAC OR CEREBRAL CIRCULATORY DISEASE AND RENAL DISEASE | ZENECA LIMITED (GB) | 2000-07-04 | — | — | US | claimed |
| US-6037341-A | HAVING POTENT ANTIMICROBIAL EFFECTS OVER GRAM-POSITIVE BACTERIA AND GRAM-NEGATIVE BACTERIA | EISAI CO., LTD. (JP) | 2000-03-14 | — | — | US | claimed |
| EP-0752986-B1 | N-HETEROCYCLYL SULPHONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LTD (GB) | 1999-05-19 | — | — | EP | claimed |
| US-5861401-A | TREATMENT OF CONGESTIVE HEART FAILURE | ZENECA LIMITED (GB) | 1999-01-19 | — | — | US | claimed |
| US-5856556-A | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | claimed |
| EP-0832082-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1998-04-01 | — | — | EP | claimed |
| JP-H09510987-A | — | — | 1997-11-04 | — | — | JP | claimed |
| US-5679800-A | DISPERSE DYES AND INTERMEDIATES FOR DISPERSE DYES | CLARIANT FINANCE (BVI) LIMITED (VG) | 1997-10-21 | — | — | US | claimed |
| EP-0499414-A2 | Pyridine derivatives as angiotensin II antagonists, processes for their preparation and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 1992-08-19 | — | — | EP | claimed |
| US-5130318-A | Hypotensive agents and for treatment of congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-14 | — | — | US | claimed |
| EP-0453210-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | claimed |
| US-4962104-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | claimed |
| EP-0374559-A2 | Substituted-2-phenyl-2,2-difluoroethyl thiocarbonates, process for their preparation and their use as herbicides | BAYER AG (DE) | 1990-06-27 | — | — | EP | claimed |
| US-4736055-A | STARING MATERIAL FOR PHOTORESIST POLYMERS | CIBA-GEIGY CORPORATION (US) | 1988-04-05 | — | — | US | claimed |
| EP-0069069-B1 | POLYMERISABLE COMPOSITIONS AND POLYMERISATION PRODUCTS RESULTING THEREFROM | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | claimed |
| EP-0069069-A2 | Polymerisable compositions and polymerisation products resulting therefrom | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | claimed |
| US-4148895-A | HYPOTENSIVE, ANTIARRHYMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | claimed |
| US-3935213-A | Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives | PFIZER INC. (US) | 1976-01-27 | — | — | US | claimed |