SCHEMBL4187850

SCHEMBL4187850

CCCCCC(N(C)C)N(CC)CC

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G1B P04054 1/20 0.47
PLA2G2A P14555 1/20 0.47
LMNA P02545 1/20 0.39
DNM1 Q05193 5/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
OPRM1 P35372 1/20 0.37
GPR84 Q9NQS5 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18315365 0.93 DNM1 (0.40) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL6455804 0.87 PLA2G1B (0.52) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL4189025 0.87 PLA2G1B (0.52) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL18315362 0.87 PLA2G1B (0.52) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL6049165 0.85 TSHR (0.47) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL125535 0.85 TSHR (0.47) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL8746175 0.85 TSHR (0.47) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL9413080 0.85 TSHR (0.47) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL9166797 0.85 TSHR (0.47) PLA2G1BPLA2G2ALMNADNM1TSHR
SCHEMBL6452480 0.85 TSHR (0.47) PLA2G1BPLA2G2ALMNADNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170174800-A1 Partially Quaternized Styrene-Based Copolymer, Ionic-Conductivity Imparter, Catalytic Electrode Layer, Membrane/Electrode Assembly and Process for Producing Same, Gas Diffusion Electrode and Process for Producing Same, and Fuel Cell of Anion Exchange Membrane Type TOKUYAMA CORPORATION (JP) 2017-06-22 US disclosed
EP-3106476-A1 PARTIALLY QUATERNIZED STYRENE-BASED COPOLYMER, IONIC-CONDUCTIVITY IMPARTER, CATALYTIC ELECTRODE LAYER, MEMBRANE/ELECTRODE ASSEMBLY AND PROCESS FOR PRODUCING SAME, GAS DIFFUSION ELECTRODE AND PROCESS FOR PRODUCING SAME, AND FUEL CELL OF ANION EXCHANGE MEMBRANE TYPE Tokuyama Corporation (JP) 2016-12-21 EP disclosed
EP-1707263-B1 Catalyst composition comprising an alkylene diamine-nickel complex and process for producing a cross-coupled compound using the same TOSOH CORP (JP) 2009-02-25 EP disclosed
US-20060224011-A1 Catalyst composition and process for producing cross-coupled compound using same TOSOH CORPORATION 2006-10-05 US disclosed
EP-1707263-A1 Catalyst composition comprising an alkylene diamine-nickel complex and process for producing a cross-coupled compound using the same Tosoh Corporation (JP) 2006-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060224011-A1 Catalyst composition and process for producing cross-coupled compound using same C5, TST, PYM1 PLA2G1B 3157/4885PLA2G2A 3644/4885LMNA 4553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.