⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31281300 | 0.82 | — | — | |
| SCHEMBL31372642 | 0.80 | LIPG (0.33) | — | |
| SCHEMBL28737605 | 0.80 | LIPG (0.33) | — | |
| SCHEMBL28925045 | 0.77 | — | — | |
| SCHEMBL31426291 | 0.77 | GAA (0.32) | — | |
| SCHEMBL13674566 | 0.76 | S1PR1 (0.47) | — | |
| SCHEMBL27750599 | 0.75 | NPC1 (0.32) | — | |
| SCHEMBL31279666 | 0.75 | DNTT (0.32) | — | |
| SCHEMBL11520528 | 0.75 | DNTT (0.32) | — | |
| SCHEMBL28888351 | 0.75 | DNTT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363432-B1 | NON-AQUEOUS PATCH | ITOCHU CHEMICAL FRONTIER CORP (JP) | 2020-12-23 | — | — | EP | disclosed |
| EP-3363432-A1 | NON-AQUEOUS PATCH | Itochu Chemical Frontier Corporation (JP) | 2018-08-22 | — | — | EP | disclosed |
| EP-2823815-B1 | NON-AQUEOUS PATCH | ITOCHU CHEMICAL FRONTIER CORP (JP) | 2018-07-04 | — | — | EP | disclosed |
| EP-1980256-B1 | OIL-IN-WATER TYPE EMULSION LOTION CONTAINING 22-OXA-1 alpha ,25-DIHYDROXYVITAMIN D3 AND METHOD OF TREATING SKIN DISEASE BY USING THE SAME | MARUHO KK (JP) | 2017-04-19 | — | — | EP | disclosed |
| EP-2823815-A1 | NON-AQUEOUS PATCH | Itochu Chemical Frontier Corporation (JP) | 2015-01-14 | — | — | EP | disclosed |
| US-8664205-B2 | Oil-in-water emulsion lotion containing 22-oxa-1α, 25-dihydroxyvitamin D3 and method of treatment of skin disorder using the same | MARUHO CO., LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-20090176749-A1 | OIL-IN-WATER EMULSION LOTION CONTAINING 22-OXA-1ALPHA, 25-DIHYDROXYVITAMIN D3 AND METHOD OF TREATMENT OF SKIN DISORDER USING THE SAME | MARUHO CO., LTD. (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1980256-A1 | OIL-IN-WATER TYPE EMULSION LOTION CONTAINING 22-OXA-1 alpha ,25-DIHYDROXYVITAMIN D3 AND METHOD OF TREATING SKIN DISEASE BY USING THE SAME | MARUHO Co., Ltd. (JP) | 2008-10-15 | — | — | EP | disclosed |