SCHEMBL4188873

SCHEMBL4188873

C=CC(=O)OCCCOc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 3/20 0.37
TSHR P16473 2/20 0.37
ALDH1A1 P00352 4/20 0.36
CYP3A4 P08684 1/20 0.36
KDM4E B2RXH2 4/20 0.35
TDP1 Q9NUW8 3/20 0.35
MAPT P10636 2/20 0.35
POLB P06746 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
APP P05067 1/20 0.33
IGF2BP2 Q9Y6M1 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PDE6D O43924 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29315676 0.98 THRB (0.46) THRBNPC1RAB9ALMNAHPGD
SCHEMBL29315681 0.97 THRB (0.45) THRBNPC1RAB9ALMNAHPGD
SCHEMBL29315679 0.97 THRB (0.45) THRBNPC1RAB9ALMNAHPGD
SCHEMBL4189444 0.94 THRB (0.53) THRBNPC1RAB9ALMNAHPGD
SCHEMBL29315723 0.90 NPC1 (0.41) THRBNPC1RAB9ALMNAHPGD
SCHEMBL29315728 0.87 NPC1 (0.40) THRBNPC1RAB9ALMNAHPGD
SCHEMBL29315727 0.87 NPC1 (0.40) THRBNPC1RAB9ALMNAHPGD
SCHEMBL29315721 0.86 NPC1 (0.42) THRBNPC1RAB9ALMNAHPGD
SCHEMBL29315693 0.86 NPC1 (0.42) THRBNPC1RAB9ALMNATSHR
SCHEMBL29315690 0.86 NPC1 (0.41) THRBNPC1RAB9ALMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
EP-3124525-B1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE TEIJIN LTD (JP) 2020-11-04 EP disclosed
US-9758630-B2 Polymer substrate with hard coat layer and manufacturing method for such polymer substrate TEIJIN LIMITED (JP) 2017-09-12 US disclosed
US-20170107345-A1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE TEIJIN LIMITED (JP) 2017-04-20 US disclosed
EP-3124525-A1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE Teijin Limited (JP) 2017-02-01 EP disclosed
EP-1995056-B1 MULTILAYER BODY TEIJIN CHEMICALS LTD (JP) 2016-08-17 EP disclosed
EP-1516722-B1 ACRYLIC RESIN COMPOSITION, ORGANOSILOXANE RESIN COMPOSITION AND LAMINATES MADE BY USING THEM TEIJIN CHEMICALS LTD (JP) 2015-09-02 EP disclosed
US-8859099-B2 Laminate of an acrylic resin composition layer containing triazine based ultra-violet compounds and an organosiloxane resin composition layer TEIJIN CHEMICALS, LTD. (JP) 2014-10-14 US disclosed
US-8765891-B2 Laminate of an acrylic resin composition layer containing triazine based ultra-violet compounds and an organosiloxane resin composition layer TEIJIN CHEMICALS, LTD. (JP) 2014-07-01 US disclosed
US-20130165570-A1 LAMINATE OF AN ACRYLIC RESIN COMPOSITION LAYER CONTAINING TRIAZINE BASED ULTRA-VIOLET COMPOUNDS AND AN ORGANOSILOXANE RESIN COMPOSITION LAYER TEIJIN CHEMICALS, LTD. (JP) 2013-06-27 US disclosed
US-8404349-B2 Laminate of an acrylic resin composition layer containing triazine based ultra-violet compounds and an organosiloxane resin composition layer TEIJIN CHEMICALS, LTD. (JP) 2013-03-26 US disclosed
EP-2511093-A1 Multilayer body Teijin Chemicals, Ltd. (JP) 2012-10-17 EP disclosed
US-20090104447-A1 Laminate TEIJIN CHEMICALS, LTD. (JP) 2009-04-23 US disclosed
EP-1995056-A1 MULTILAYER BODY Teijin Chemicals, Ltd. (JP) 2008-11-26 EP disclosed
US-7070859-B2 Acrylic resin composition organosiloxane resin composition and laminate comprising the same TEIJIN CHEMICALS, LTD. (JP) 2006-07-04 US disclosed
EP-1516722-A1 ACRYLIC RESIN COMPOSITION, ORGANOSILOXANE RESIN COMPOSITION AND LAMINATES MADE BY USING THEM Teijin Chemicals, Ltd. (JP) 2005-03-23 EP disclosed
US-20040247878-A1 Acrylic resin composition organosiloxane resin composition and laminate comprising the same TEIJIN CHEMICALS LTD. (JP) 2004-12-09 US disclosed