Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 7/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29315728 | 1.00 | NPC1 (0.40) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL29315723 | 0.97 | NPC1 (0.41) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL29315721 | 0.95 | NPC1 (0.42) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL29315679 | 0.91 | THRB (0.45) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL29315681 | 0.91 | THRB (0.45) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL29315690 | 0.90 | NPC1 (0.41) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL29315724 | 0.90 | NPC1 (0.41) | NPC1RAB9ALMNAALDH1A1IGF2BP2 | |
| SCHEMBL29315676 | 0.89 | THRB (0.46) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL4188873 | 0.87 | THRB (0.46) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL299318 | 0.84 | NPC1 (0.51) | NPC1RAB9ALMNAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |