Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176964 | 0.87 | ALDH1A1 (0.51) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4985771 | 0.83 | CYP1A2 (0.59) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4985765 | 0.83 | CYP1A2 (0.59) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4977949 | 0.82 | ALDH1A1 (0.60) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4977941 | 0.82 | ALDH1A1 (0.60) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4191194 | 0.80 | CHRM3 (0.53) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4176854 | 0.79 | CHRM3 (0.56) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4184498 | 0.78 | ALDH1A1 (0.67) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4184606 | 0.78 | CYP1A2 (0.51) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 | |
| SCHEMBL4184609 | 0.78 | CYP1A2 (0.51) | CYP1A2ALDH1A1CYP3A4CYP2D6CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137623-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137623-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | CHRM2, CHRM1, CHRM5 | CYP1A2 189/4885ALDH1A1 698/4885CYP3A4 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.