SCHEMBL4189246

SCHEMBL4189246

CCC(=O)NCCNC(=O)Nc1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)ccc1C

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4203215 0.94 FASN (0.62) FASN
SCHEMBL4203140 0.92 FASN (0.60) FASN
SCHEMBL4201403 0.92 FASN (0.65) FASN
SCHEMBL4191299 0.92 FASN (0.60) FASN
SCHEMBL4203620 0.91 FASN (0.62) FASN
SCHEMBL4200349 0.91 FASN (0.62) FASN
SCHEMBL4196956 0.91 FASN (0.60) FASN
SCHEMBL4199582 0.91 FASN (0.61) FASN
SCHEMBL4204935 0.90 FASN (0.63) FASN
SCHEMBL4199034 0.90 FASN (0.62) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090118332-A1 Therapeutic Agents - 551 ASTRAZENECA AB (SE) 2009-05-07 US disclosed
US-20090118332-A1 Therapeutic Agents - 551 ASTRAZENECA AB (SE) 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118332-A1 Therapeutic Agents - 551 GPR119, FABP4, FASN FASN 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.