Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.72 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189469 | 0.86 | MAPK9 (0.68) | MAPK9MAPK10MEN1KMT2ARXFP1 | |
| SCHEMBL2425338 | 0.85 | MAPK9 (0.72) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL1518774 | 0.85 | MAPK9 (1.00) | MAPK9MAPK10MEN1KMT2ARXFP1 | |
| SCHEMBL2420939 | 0.85 | MAPK9 (0.63) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL4970923 | 0.84 | MAPK9 (0.79) | MAPK9MAPK10MEN1KMT2ARXFP1 | |
| SCHEMBL2422524 | 0.84 | MAPK9 (0.81) | MAPK9MAPK10MEN1KMT2ARXFP1 | |
| SCHEMBL2422088 | 0.84 | MAPK9 (0.81) | MAPK9MAPK10MEN1KMT2ARXFP1 | |
| SCHEMBL2422850 | 0.81 | MAPK9 (0.75) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2420683 | 0.81 | MAPK9 (0.85) | MAPK9MAPK10MEN1KMT2ARXFP1 | |
| SCHEMBL7886289 | 0.80 | MAPK9 (0.65) | MAPK9MAPK10MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |