SCHEMBL4189770

SCHEMBL4189770

COCCN1CCN(CCO)C1=O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SCN9A Q15858 1/20 0.36
PARP1 P09874 1/20 0.35
GBA1 P04062 2/20 0.34
P2RX7 Q99572 1/20 0.34
ATM Q13315 1/20 0.33
MMP1 P03956 1/20 0.32
MMP3 P08254 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 1/20 0.32
RGS4 P49798 1/20 0.32
RGS8 P57771 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14094214 0.90 ALDH1A1 (0.42) ALDH1A1SCN9APARP1P2RX7ATM
SCHEMBL9972952 0.85 KMT2A (0.36) MEN1KMT2AMAPT
SCHEMBL3191229 0.83 KMT2A (0.39) ALDH1A1MEN1KMT2APARP1MAPT
SCHEMBL14094220 0.82 ALDH1A1 (0.39) ALDH1A1SCN9APARP1MMP1MMP3
SCHEMBL7720084 0.81 ALDH1A1 (0.36) ALDH1A1SCN9APARP1GBA1P2RX7
SCHEMBL10851567 0.81 SCN9A (0.38) ALDH1A1SCN9APARP1P2RX7ATM
SCHEMBL4200622 0.81 ALDH1A1 (0.36) ALDH1A1SCN9APARP1P2RX7ATM
SCHEMBL4194219 0.81 ALDH1A1 (0.36) ALDH1A1SCN9APARP1P2RX7ATM
SCHEMBL10847486 0.80 HTT (0.38) ALDH1A1KMT2APARP1ATMMAPT
SCHEMBL751330 0.80 ALDH1A1 (0.38) ALDH1A1SCN9APARP1P2RX7HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1361246-B1 ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND MITSUI CHEMICALS INC (JP) 2009-02-18 EP disclosed
US-6797805-B2 Organic polymers and novel polymerizable compounds MITSUI CHEMICALS, INC. (JP) 2004-09-28 US disclosed
EP-1361246-A1 ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND Mitsui Chemicals, Inc. (JP) 2003-11-12 EP disclosed
US-20030166808-A1 Organic polymers and novel polymerizable compound MITSUI CHEMICALS, INC. (JP) 2003-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166808-A1 Organic polymers and novel polymerizable compound PCNA, UTP18, ODC1 ALDH1A1 4350/4885MEN1 3941/4885KMT2A 2338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.