SCHEMBL4189786

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL4194494	0.99	ROCK2 (0.71)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL4197244	0.93	ROCK2 (0.68)	ROCK2ROCK1CCR2PRKD3PRKCG
	Hydrochloric Acid SCHEMBL4195810	0.92	ROCK2 (0.67)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL30077171	0.92	ROCK2 (0.73)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL22971795	0.92	ROCK2 (0.73)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL9880977	0.87	ROCK2 (0.66)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL13606957	0.86	ROCK2 (0.60)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL4191877	0.86	ROCK2 (0.60)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL13606959	0.86	ROCK2 (0.60)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL18085945	0.86	ROCK2 (0.67)	ROCK2ROCK1CCR2PRKD3PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.