Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 12/20 | 0.68 |
| ▸ | CA12 | O43570 | 11/20 | 0.68 |
| ▸ | CA1 | P00915 | 6/20 | 0.68 |
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.65 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.65 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.65 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.65 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.64 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.64 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.64 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176762 | 0.87 | KMT2A (0.62) | SMN1; SMN2RAB9AMAPTPOLBNPSR1 | |
| SCHEMBL17947763 | 0.84 | CA9 (0.90) | CA9CA12CA1CA2SMN1; SMN2 | |
| SCHEMBL12585053 | 0.83 | CA9 (0.79) | CA9CA12CA1CA2SMN1; SMN2 | |
| SCHEMBL10119209 | 0.82 | MAPT (0.67) | CA9CA12CA1CA2SMN1; SMN2 | |
| SCHEMBL16615487 | 0.82 | MAPT (0.69) | CA9CA12CA1CA2MAPT | |
| SCHEMBL16615501 | 0.80 | CA1 (0.67) | CA9CA12CA1CA2SMN1; SMN2 | |
| SCHEMBL6312180 | 0.80 | ABCC9 (0.62) | CA9CA12CA1CA2SMN1; SMN2 | |
| SCHEMBL16615520 | 0.80 | MAPT (0.66) | CA9CA12CA1RAB9AMAPT | |
| SCHEMBL16615819 | 0.79 | LMNA (0.64) | CA9CA12CA1SMN1; SMN2RAB9A | |
| SCHEMBL16615503 | 0.79 | CA12 (0.61) | CA9CA12CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED | 2009-09-10 | — | — | US | claimed |
| WO-2007005887-A2 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS, COMPOSITIONS AND USES THEREOF | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-01-11 | — | — | WO | claimed |
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED | 2009-09-10 | — | — | US | disclosed |
| WO-2007005887-A2 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS, COMPOSITIONS AND USES THEREOF | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | AR, NR5A1, ESRRA | CA9 2903/4885CA12 3565/4885CA1 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.