Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 4/20 | 0.49 |
| ▸ | PAK2 | Q13177 | 3/20 | 0.49 |
| ▸ | SIK2 | Q9H0K1 | 4/20 | 0.48 |
| ▸ | STK4 | Q13043 | 3/20 | 0.48 |
| ▸ | STK3 | Q13188 | 3/20 | 0.48 |
| ▸ | STK26 | Q9P289 | 3/20 | 0.48 |
| ▸ | STK24 | Q9Y6E0 | 3/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCND2 | P30279 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179462 | 0.87 | PAK1 (0.48) | PAK1PAK2SIK2STK4STK3 | |
| SCHEMBL4737969 | 0.83 | LYN (0.45) | PAK1SIK2CDK4CCND1CCND2 | |
| SCHEMBL29498221 | 0.82 | RIPK2 (0.57) | SIK2STK4STK3STK26STK24 | |
| SCHEMBL20563509 | 0.82 | RIPK2 (0.57) | SIK2STK4STK3STK26STK24 | |
| SCHEMBL4181003 | 0.82 | PAK1 (0.51) | PAK1PAK2SIK2STK4STK3 | |
| SCHEMBL4169067 | 0.81 | TNK2 (0.45) | PAK1PAK2SIK2STK4STK3 | |
| SCHEMBL22191283 | 0.79 | ALDH1A1 (0.42) | SIK2STK4STK3STK26STK24 | |
| SCHEMBL29352983 | 0.79 | ALDH1A1 (0.42) | SIK2STK4STK3STK26STK24 | |
| SCHEMBL22191244 | 0.77 | CYP1A2 (0.44) | PAK1PAK2SIK2STK4STK3 | |
| SCHEMBL29353887 | 0.77 | CYP1A2 (0.44) | PAK1PAK2SIK2STK4STK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036472-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-02-05 | — | — | US | disclosed |
| EP-1846403-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | Ranbaxy Laboratories Limited (IN) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006082492-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036472-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | IL1B, TPMT, IL1R1 | PAK1 783/4885PAK2 1485/4885SIK2 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.